Aminoglycosides (AGs) are long-known molecules successfully used against Gram-negative
pathogens. While their use declined with the discovery of new antibiotics, they are now …

Novel antibacterial therapies are urgently required to tackle the increasing number of
multidrug‐resistant pathogens. Identification of new antimicrobial targets is critical to avoid …

Most cancer‐related deaths result from the progressive growth of metastases. Patients with
peritoneal metastatic (PM) colorectal cancer have reduced overall survival. Currently, it is …

Salmonella enterica is a food-borne pathogen that poses a severe threat to both poultry
production and human health. Antibiotics are critical for the initial treatment of bacterial …

The emergence of antibiotic tolerance enables genetically susceptible bacteria to withstand
the killing by clinically relevant antibiotics. As is reported, an increasing body of evidence …

Acinetobacter infections have high rates of mortality due to an increasing incidence of
infections by multidrug-resistant (MDR) and extensively-drug-resistant (XDR) strains …

Antimicrobial peptides (AMPs) are a developing class of natural and synthetic oligopeptides
with host defense mechanisms against a broad spectrum of microorganisms. With in‐depth …

Bacterial antibiotic resistance, especially the emergence of multidrug-resistant (MDR)
strains, urgently requires the development of effective treatment strategies. It is always of …

Following the discovery of streptomycin from Streptomyces griseus in the 1940s by Selman
Waksman and colleagues, aminoglycosides were first used to treat tuberculosis and then …

The emergence and prevalence of mobile colistin resistance gene mcr have dramatically
compromised the clinical efficacy of colistin, a cyclopeptide antibiotic considered to be the …