Its increasing incidence has led stroke to be the second leading cause of death worldwide.
Despite significant advances in recanalization strategies, patients are still at risk for …

Immunological mechanisms have come into the focus of current translational stroke
research, and the modulation of neuroinflammatory pathways has been identified as a …

Inflammation and immune mechanisms are crucially involved in the pathophysiology of the
development, acute damage cascades, and chronic course after ischemic stroke …

Stroke produces a powerful inflammatory cascade in the brain, but also a suppression of the
peripheral immune system, which is also called stroke-induced immunosuppression (SIIS) …

The pleiotropic cytokine interleukin-6 (IL-6) is emerging as a molecule with both beneficial
and destructive potentials. It can exert opposing actions triggering either neuron survival …

Stroke is currently one of the most common causes of death and disability in the world, and
its pathophysiology is a complex process, involving the oxidative stress and inflammatory …

Background and Purpose—The proinflammatory cytokine IL-1 (interleukin-1) has a
deleterious role in cerebral ischemia, which is attenuated by IL-1 receptor antagonist (IL …

Stroke-associated pneumonia is a frequent complication after stroke associated with poor
outcome. Dysphagia is a known risk factor for stroke-associated pneumonia but …

After an acute ischemic stroke (AIS), inflammatory processes are able to concomitantly
induce both beneficial and detrimental effects. In this narrative review, we updated evidence …

Background and Purpose—Stroke diagnosis could be challenging in the acute phase. We
aimed to develop a blood-based diagnostic tool to differentiate between real strokes and …