SLC6 neurotransmitter transporters: structure, function, and regulation
AS Kristensen, J Andersen, TN Jørgensen… - Pharmacological …, 2011 - Elsevier
The neurotransmitter transporters (NTTs) belonging to the solute carrier 6 (SLC6) gene
family (also referred to as the neurotransmitter-sodium-symporter family or Na+/Cl …
family (also referred to as the neurotransmitter-sodium-symporter family or Na+/Cl …
Plasma membrane monoamine transporters: structure, regulation and function
The classical biogenic amine neurotransmitters—dopamine, noradrenaline, and 5-
hydroxytryptamine—control a variety of functions including locomotion, autonomic function …
hydroxytryptamine—control a variety of functions including locomotion, autonomic function …
Multi-target strategies for the improved treatment of depressive states: conceptual foundations and neuronal substrates, drug discovery and therapeutic application
MJ Millan - Pharmacology & therapeutics, 2006 - Elsevier
Major depression is a debilitating and recurrent disorder with a substantial lifetime risk and a
high social cost. Depressed patients generally display co-morbid symptoms, and depression …
high social cost. Depressed patients generally display co-morbid symptoms, and depression …
Pharmaceuticals as neuroendocrine disruptors: lessons learned from fish on Prozac
JA Mennigen, P Stroud, JM Zamora… - Journal of Toxicology …, 2011 - Taylor & Francis
Pharmaceuticals are increasingly detected in a variety of aquatic systems. One of the most
prevalent environmental pharmaceuticals in North America and Europe is the …
prevalent environmental pharmaceuticals in North America and Europe is the …
Movement disorders and neurochemical changes in zebrafish larvae after bath exposure to fluoxetine (PROZAC)
MJ Airhart, DH Lee, TD Wilson, BE Miller… - Neurotoxicology and …, 2007 - Elsevier
This study examines the effects of the selective serotonin reuptake inhibitor (SSRI),
fluoxetine (PROZAC), on the ontogeny of spontaneous swimming activity (SSA) in …
fluoxetine (PROZAC), on the ontogeny of spontaneous swimming activity (SSA) in …
The S-enantiomer of R, S-citalopram, increases inhibitor binding to the human serotonin transporter by an allosteric mechanism. Comparison with other serotonin …
F Chen, MB Larsen, C Sánchez, O Wiborg - European …, 2005 - Elsevier
The interaction of the S-and R-enantiomers (escitalopram and R-citalopram) of citalopram,
with high-and low-affinity binding sites in COS-1 cell membranes expressing human SERT …
with high-and low-affinity binding sites in COS-1 cell membranes expressing human SERT …
Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants
LK Henry, JR Field, EM Adkins, ML Parnas… - Journal of Biological …, 2006 - ASBMB
In previous studies examining the structural determinants of antidepressant and substrate
recognition by serotonin transporters (SERTs), we identified Tyr-95 in transmembrane …
recognition by serotonin transporters (SERTs), we identified Tyr-95 in transmembrane …
An AOP analysis of selective serotonin reuptake inhibitors (SSRIs) for fish
MD McDonald - Comparative Biochemistry and Physiology Part C …, 2017 - Elsevier
Pharmaceuticals and personal care products (PPCPs) are found in measureable quantities
within the aquatic environment. Selective serotonin reuptake inhibitor (SSRI) …
within the aquatic environment. Selective serotonin reuptake inhibitor (SSRI) …
Density and function of central serotonin (5‐HT) transporters, 5‐HT1A and 5‐HT2A receptors, and effects of their targeting on BTBR T+tf/J mouse social behavior
GG Gould, JG Hensler, TF Burke… - Journal of …, 2011 - Wiley Online Library
J. Neurochem.(2011) 116, 291–303. Abstract BTBR mice are potentially useful tools for
autism research because their behavior parallels core social interaction impairments and …
autism research because their behavior parallels core social interaction impairments and …
Physiological endpoints for potential SSRI interactions in fish
N Kreke, DR Dietrich - Critical reviews in toxicology, 2008 - Taylor & Francis
Selective serotonin reuptake inhibitors (SSRIs) are among the pharmaceutical compounds
frequently detected in sewage treatment plant effluents and surface waters, albeit at very low …
frequently detected in sewage treatment plant effluents and surface waters, albeit at very low …