Transmissible cancers are infectious parasitic clones that metastasize to new hosts, living
past the death of the founder animal in which the cancer initiated. We investigated the …

Clonal hematopoiesis (CH), in which hematopoietic stem and progenitor cell (HSPC) clones
and their progeny expand in the circulating blood cell population, occurs following the …

SUMMARY A growing number of studies have applied evolutionary and ecological
principles to understanding cancer. However, few such studies have examined whether …

Coevolution is common and frequently governs host–pathogen interaction outcomes.
Phenotypes underlying these interactions often manifest as the combined products of the …

Genetic variation is a well-known contributor to the onset and progression of cancer. The
goal of this study is to provide a comprehensive examination of the nucleotide and …

Ecology and biogeography of bivalve transmissible neoplasia (BTN) are underexplored due
to its recent discovery and a challenging diagnostics. Blue mussels harbour two evolutionary …

Emerging new mutations after treatment can provide clues to acquired resistant
mechanisms. Circulating tumor DNA (ctDNA) sequencing has enabled noninvasive …

Emerging infectious diseases threaten natural populations, and data-driven modeling is
critical for predicting population dynamics. Despite the importance of integrating ecology …

Background and Aim: Canine transmissible venereal tumor (CTVT), a unique transmissible
cancer in dogs, affects the external genitalia and potentially spreads to other parts of the …

We performed WES of 250 unique tumor tissues from 30 multiregion sampled pancreatic
cancer research autopsies from patients diagnosed with advanced stage disease. We find …