Drug resistance and treatment failure in leishmaniasis: A 21st century challenge

A Ponte-Sucre, F Gamarro, JC Dujardin… - PLoS neglected …, 2017 - journals.plos.org
Reevaluation of treatment guidelines for Old and New World leishmaniasis is urgently
needed on a global basis because treatment failure is an increasing problem. Drug …

One health approach to leishmaniases: understanding the disease dynamics through diagnostic tools

A Hong, RA Zampieri, JJ Shaw, LM Floeter-Winter… - Pathogens, 2020 - mdpi.com
Leishmaniases are zoonotic vector-borne diseases caused by protozoan parasites of the
genus Leishmania that affect millions of people around the globe. There are various clinical …

Xenodiagnosis to evaluate the infectiousness of humans to sandflies in an area endemic for visceral leishmaniasis in Bihar, India: a transmission-dynamics study

OP Singh, P Tiwary, AK Kushwaha, SK Singh… - The Lancet …, 2021 - thelancet.com
Background Visceral leishmaniasis, also known on the Indian subcontinent as kala-azar, is
a fatal form of leishmaniasis caused by the protozoan parasite Leishmania donovani and …

Current challenges in treatment options for visceral leishmaniasis in India: a public health perspective

O Prakash Singh, B Singh, J Chakravarty… - Infectious diseases of …, 2016 - mednexus.org
Visceral leishmaniasis (VL) is a serious parasitic disease causing considerable mortality
and major disability in the Indian subcontinent. It is most neglected tropical disease …

Global genome diversity of the Leishmania donovani complex

SU Franssen, C Durrant, O Stark, B Moser, T Downing… - Elife, 2020 - elifesciences.org
Protozoan parasites of the Leishmania donovani complex–L. donovani and L. infantum–
cause the fatal disease visceral leishmaniasis. We present the first comprehensive genome …

Asymptomatic Leishmania Infection: A New Challenge for Leishmania Control

OP Singh, E Hasker, D Sacks… - Clinical Infectious …, 2014 - academic.oup.com
Asymptomatic Leishmania Infection: A New Challenge for Leishmania Control | Clinical
Infectious Diseases | Oxford Academic Skip to Main Content Advertisement Oxford Academic …

Immunobiology of visceral leishmaniasis

R Kumar, S Nylén - Frontiers in immunology, 2012 - frontiersin.org
Visceral leishmaniasis (VL), commonly known as kala-azar, is caused by Leishmania
donovani and Leishmania infantum (Leishmania chagasi in the Americas). These …

Rapid tests for the diagnosis of visceral leishmaniasis in patients with suspected disease

M Boelaert, K Verdonck, J Menten… - Cochrane database …, 2014 - cochranelibrary.com
Background The diagnosis of visceral leishmaniasis (VL) in patients with fever and a large
spleen relies on showing Leishmania parasites in tissue samples and on serological tests …

Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent

H Imamura, T Downing, F Van den Broeck, MJ Sanders… - Elife, 2016 - elifesciences.org
Leishmania donovani causes visceral leishmaniasis (VL), the second most deadly vector-
borne parasitic disease. A recent epidemic in the Indian subcontinent (ISC) caused up to …

Laboratory diagnosis of cutaneous and visceral leishmaniasis: current and future methods

JQ Reimão, EM Coser, MR Lee, AC Coelho - Microorganisms, 2020 - mdpi.com
Leishmaniasis is a neglected tropical disease with two main clinical forms: cutaneous and
visceral leishmaniasis. Diagnosis of leishmaniasis is still a challenge, concerning the …