Aging is a complex process that results in loss of the ability to reattain homeostasis following
stress, leading, thereby, to increased risk of morbidity and mortality. Many factors contribute …

Cancer diagnostics and therapies have improved steadily over the last few decades,
markedly increasing life expectancy for patients at all ages. However, conventional and …

ESC Guidelines e341 (1) the specific situation of the patient. In this respect, it is specified
that, unless otherwise provided for by national regulations, offlabel use of medication should …

The considerable progress made in the field of cancer treatment has led to a dramatic
improvement in the prognosis of patients with cancer. However, toxicities resulting from …

Background The past few decades have seen substantial improvements in cancer survival,
but concerns exist about long-term cardiovascular disease risk in survivors. Evidence is …

Importance Echocardiographic left ventricular global longitudinal strain (GLS) detects early
subclinical ventricular dysfunction and can be used in patients receiving potentially …

Importance Anthracyclines are part of many effective pediatric cancer treatment protocols.
Most pediatric oncology treatment groups assume that the hematologic toxicity of …

Cardiac diseases in the growing population of childhood cancer survivors are of major
concern. Cardiotoxicity as a consequence of anthracyclines and chest radiotherapy …

Background The objective of this study was to examine long‐term outcomes among children
newly diagnosed with cancer who were treated in dexrazoxane‐containing clinical trials …

PURPOSE For survivors of childhood cancer treated with doxorubicin, dexrazoxane is
cardioprotective for at least 5 years. However, longer-term data are lacking. METHODS …