There are concepts in science that need time to overcome initial disbelief before finally
arriving at the moment when they are embraced by the research community. One of these …

The scientific community faces an unexpected and urgent challenge related to the SARS-
CoV-2 pandemic and is investigating the role of receptors involved in entry of this virus into …

With a growing aged population, there is an imminent need to develop new therapeutic
strategies to ameliorate disorders of hematopoietic aging, including clonal hematopoiesis …

Inflammation is involved in tumor development and progression as well as antitumor
response to therapy. In the past decade, the crosstalk between inflammation, immunity, and …

Abstract Angiotensin-converting enzyme 2 (ACE2) plays an important role as a member of
the renin–angiotensin–aldosterone system (RAAS) in regulating the conversion of …

Scientists and health professionals are exhaustively trying to contain the coronavirus
disease 2019 (COVID-19) pandemic by elucidating viral invasion mechanisms, possible …

Inflammation, when properly mounted and precisely calibrated, is a beneficial process that
enables the rapid removal of invading pathogens and/or cellular corpses and promotes …

IRAK-targeted therapies that have matriculated to early phase trials are yielding promising
preliminary results. However, studies of IRAK kinase signaling continue to defy conventional …

Adaptive CD4+ T helper cells and their innate counterparts, innate lymphoid cells, utilize an
identical set of transcription factors (TFs) for their differentiation and functions. However …

Hematopoietic stem and progenitor cells (HSPCs) are responsible for lifelong maintenance
of hematopoiesis through self-renewal and differentiation into mature blood cell lineages …