Function of sperm chromatin structural elements in fertilization and development
WS Ward - MHR: Basic science of reproductive medicine, 2009 - academic.oup.com
Understanding how DNA is packaged in the mammalian sperm cell has important
implications for human infertility as well as for the cell biology. Recent advances in the study …
implications for human infertility as well as for the cell biology. Recent advances in the study …
The controversy, potential and roles of spermatozoal RNA
D Miller, GC Ostermeier, SA Krawetz - Trends in molecular medicine, 2005 - cell.com
The majority of cellular and molecular andrologists endorse the view that the sperm is a
vessel for transporting the paternal genome to the waiting egg and nothing more. Any …
vessel for transporting the paternal genome to the waiting egg and nothing more. Any …
[HTML][HTML] The 3D structure of the immunoglobulin heavy-chain locus: implications for long-range genomic interactions
The immunoglobulin heavy-chain (Igh) locus is organized into distinct regions that contain
multiple variable (VH), diversity (DH), joining (JH) and constant (CH) coding elements. How …
multiple variable (VH), diversity (DH), joining (JH) and constant (CH) coding elements. How …
Chromatin loops are selectively anchored using scaffold/matrix-attachment regions
The biological significance of nuclear scaffold/matrix-attachment regions (S/MARs) remains
a topic of long-standing interest. The key to understanding S/MAR behavior relies on …
a topic of long-standing interest. The key to understanding S/MAR behavior relies on …
Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cells
The immunoglobulin heavy-chain (IgH) locus undergoes large-scale contraction in B cells
poised to undergo IgH V (D) J recombination. We considered the possibility that looping of …
poised to undergo IgH V (D) J recombination. We considered the possibility that looping of …
On a chromosome far, far away: LCRs and gene expression
A Dean - TRENDS in Genetics, 2006 - cell.com
Transcription activation of a gene involves the ordered recruitment of components of the
basal transcription machinery in concert with alterations in chromatin structure, including …
basal transcription machinery in concert with alterations in chromatin structure, including …
Quantification of epigenetic DNA modifications in the subchromatin structure matrix attachment regions by stable isotope dilution UHPLC-MS/MS analysis
R Zhang, W Lai, H Wang - Analytical Chemistry, 2021 - ACS Publications
To date, subchromatin structure-based quantification of epigenetic DNA modifications is
limited. Matrix attachment regions (MARs), an important subchromatin structure, contain …
limited. Matrix attachment regions (MARs), an important subchromatin structure, contain …
SATB1 family protein expressed during early erythroid differentiation modifies globin gene expression
J Wen, S Huang, H Rogers, LA Dickinson… - Blood, 2005 - ashpublications.org
Special AT-rich binding protein 1 (SATB1) nuclear protein, expressed predominantly in T
cells, regulates genes through targeting chromatin remodeling during T-cell maturation …
cells, regulates genes through targeting chromatin remodeling during T-cell maturation …
[HTML][HTML] Nuclear matrix interactions at the human protamine domain: a working model of potentiation
The compact eukaryotic genome must be selectively opened to grant trans-factor access to
cis-regulatory elements to overcome the primary barrier to gene transcription. The …
cis-regulatory elements to overcome the primary barrier to gene transcription. The …
[HTML][HTML] Genomic mapping of RNA polymerase II reveals sites of co-transcriptional regulation in human cells
Background Transcription by RNA polymerase II is regulated at many steps including
initiation, promoter release, elongation and termination. Accumulation of RNA polymerase II …
initiation, promoter release, elongation and termination. Accumulation of RNA polymerase II …