There are many restrictions on topical medications for the oral cavity. Various factors affect
the topical application of drugs in the oral cavity, an open and complex environment. The …

Designing 3D constructs with appropriate materials and structural frameworks for complex
dental restorative/regenerative procedures has always remained a multi-criteria optimization …

The pain and fear caused by direct local injection of anesthetic or the poor experience with
surface anesthetic cream increase the difficulty of clinical treatment for oral diseases. To …

There has been increasing interest and rapid developments in precision medicine, which is
a new medical concept and model based on individualized medicine with the joint …

There are several routes of drug administration, and each one has advantages and
limitations. In the case of the topical application in the oral cavity, comprising the buccal …

This work describes the development of a gastroresistant antimicrobial formulation
composed of two carriers, pectin and liposomes, intended to improve the efficiency of …

Recent advances have been reported for needle-free local anesthesia in maxillary teeth by
administering a nasal spray of tetracaine (TTC) and oxymetazoline, without causing pain …

Local anesthetics, particularly amide types, play a crucial role in perioperative anesthesia to
alleviate pain and manage chronic, long-term pain, with their brief effect period remaining a …

Needle-free buccal anesthesia improves dental treatment outcomes for both patients and
dentists. In this study, we report on an assessment of the enhancement effects of α-bisabolol …

In recent years, advanced nanohybrid materials processed as pharmaceuticals have proved
to be very advantageous. Triptans, such as the commercially available intranasal …