Biodetoxification using intravenous lipid emulsion (ILE) in acute poisoning is of growing
interest. As well as for local anesthetics, ILE is currently used to reverse toxicity caused by a …

Background Despite conflicting data, intravenous lipid emulsion has emerged as a potential
antidote. The “lipid sink” theory suggests that following intravenous administration of lipid …

Background A considerable portion of acutely intoxicated patients is presented with
impaired consciousness. Early identification of those patients who require advanced …

Acute clozapine poisoning (ACP) is frequently reported worldwide. We evaluated the
efficacy of the Poison Severity Score (PSS), Acute Physiology and Chronic Health …

Infusion of lipid emulsion for drug overdose arose as a treatment for local anaesthetic
systemic toxicity (LAST) initially based on laboratory results in animal models with the …

Background Clozapine is an atypical antipsychotic drug used for the treatment of refractory
schizophrenia. It is reported as the most toxic in its class. Using serum clozapine level as a …

Intravenous lipid emulsions (ILE), among other uses, are utilized in the treatment of
poisonings caused by lipophilic substances. The body of evidence regarding the benefits of …

Clozapine has been considered the “gold standard” in the treatment of schizophrenia for
many years. Clozapine has a superior effect, particularly in the treatment of negative …

The administration of intravenous lipid emulsion (ILE) is a proven antidote used to reverse
local anesthetic-related systemic toxicity. Although the capacity of ILE to generate blood …

Background As the prevalence of tramadol toxicity is increasing, managing these patients
with the aim of treatment and complete recovery has become a major challenge for health …