Advances in vaccine development for human lymphatic filariasis
R Kalyanasundaram, V Khatri, N Chauhan - Trends in parasitology, 2020 - cell.com
According to the World Health Organization, over 880 million people are currently at risk of
acquiring lymphatic filariasis (LF) in over 52 countries worldwide. Current approaches to …
acquiring lymphatic filariasis (LF) in over 52 countries worldwide. Current approaches to …
Lymphatic filariasis vaccine development: neglected for how long?
Introduction Lymphatic filariasis (LF), also known as elephantiasis, has been recognized by
the world health organization and the centers for disease control and prevention as one of …
the world health organization and the centers for disease control and prevention as one of …
[HTML][HTML] Designing efficient multi-epitope peptide-based vaccine by targeting the antioxidant thioredoxin of bancroftian filarial parasite
Thioredoxin is a low molecular weight redox-active protein of filarial parasite that plays a
crucial role in downregulating the host immune response to prolong the survival of the …
crucial role in downregulating the host immune response to prolong the survival of the …
A recombinant La Sota vaccine strain expressing multiple epitopes of infectious bronchitis virus (IBV) protects specific pathogen-free (SPF) chickens against IBV and …
L Tan, G Wen, X Qiu, Y Yuan, C Meng, Y Sun, Y Liao… - Vaccines, 2019 - mdpi.com
Infectious bronchitis (IB) and Newcastle disease (ND) are two major infectious diseases that
are a threat to the domestic poultry industry. In this study, we successfully generated a …
are a threat to the domestic poultry industry. In this study, we successfully generated a …
Computational design and preliminary serological analysis of a novel multi-epitope vaccine candidate against onchocerciasis and related filarial diseases
RA Shey, SM Ghogomu, CM Shintouo, FN Nkemngo… - Pathogens, 2021 - mdpi.com
Onchocerciasis is a skin and eye disease that exerts a heavy socio-economic burden,
particularly in sub-Saharan Africa, a region which harbours greater than 96% of either …
particularly in sub-Saharan Africa, a region which harbours greater than 96% of either …
Moderate protection is induced by a chimeric protein composed of leucine aminopeptidase and cathepsin L1 against Fasciola hepatica challenge in sheep
S Ortega-Vargas, C Espitia, A Sahagún-Ruiz, C Parada… - Vaccine, 2019 - Elsevier
Leucine aminopeptidase (FhLAP) and cathepsin L1 (FhCL1) of Fasciola hepatica play a
critical role in parasite feeding, migration through host tissue, and immune evasion. These …
critical role in parasite feeding, migration through host tissue, and immune evasion. These …
Lymphatic filariasis and visceral leishmaniasis coinfection: A review on their epidemiology, therapeutic, and immune responses
V Kushwaha, S Kaur - Acta Tropica, 2021 - Elsevier
Coinfection is less commonly observed in individuals around the world, yet it is more
common than the single infection. Around 800 million people worldwide are infected with …
common than the single infection. Around 800 million people worldwide are infected with …
Designing of a chimeric multiepitope vaccine against bancroftian lymphatic filariasis through immunoinformatics approaches
R Parvin, M Habib Ullah Masum, J Ferdous… - Plos one, 2024 - journals.plos.org
The filarial worms of Wuchereria bancrofti are the primary cause of lymphatic filariasis (LF), a
mosquito-borne disease among the neglected tropical parasitic diseases. Considering the …
mosquito-borne disease among the neglected tropical parasitic diseases. Considering the …
Dose‐Dependent Prophylactic Efficacy of Filarial Antigens Glutathione‐S‐Transferase and Abundant Larval Transcript‐2 against Brugia malayi Challenge in …
Objective. To identify the most effective dose of filarial rBmALT‐2 and rWbGST alone or in
combination against B. malayi infection in vitro and in vivo. Methods. Mastomys (n= 5 …
combination against B. malayi infection in vitro and in vivo. Methods. Mastomys (n= 5 …
In-silico development of multi-epitope subunit vaccine against lymphatic filariasis
P Singh, S Shaikh, S Gupta, R Gupta - Journal of Biomolecular …, 2023 - Taylor & Francis
Abstract The World Health Organization in 2022 reported that more than 863 million people
in 50 countries are at risk of developing lymphatic filariasis (LF), a disease caused by …
in 50 countries are at risk of developing lymphatic filariasis (LF), a disease caused by …