Metallothionein and cadmium toxicology—Historical review and commentary

M Nordberg, GF Nordberg - Biomolecules, 2022 - mdpi.com
More than one and a half centuries ago, adverse human health effects were reported after
use of a cadmium-containing silver polishing agent. Long-term cadmium exposure gives rise …

[HTML][HTML] An overview of carcinogenic heavy metal: molecular toxicity mechanism and prevention

HS Kim, YJ Kim, YR Seo - Journal of cancer prevention, 2015 - ncbi.nlm.nih.gov
Almost all heavy metals are serious toxicants as carcinogens. However, due to their
chemical and physiological properties, heavy metals are useful in industrial areas including …

Chronic kidney disease and exposure to nephrotoxic metals

SE Orr, CC Bridges - International journal of molecular sciences, 2017 - mdpi.com
Chronic kidney disease (CKD) is a common progressive disease that is typically
characterized by the permanent loss of functional nephrons. As injured nephrons become …

Health effects of cadmium exposure–a review of the literature and a risk estimate

L Järup, M Berglund, CG Elinder, G Nordberg… - Scandinavian journal of …, 1998 - JSTOR
Health effects of cadmium exposure – a review of the literature and a risk estimate Page 1
Scand J Work Environ Health 1998;24:suppl 1:52 p. Health effects of cadmium exposure - a …

Metallothionein protection of cadmium toxicity

CD Klaassen, J Liu, BA Diwan - Toxicology and applied pharmacology, 2009 - Elsevier
The discovery of the cadmium (Cd)-binding protein from horse kidney in 1957 marked the
birth of research on this low-molecular weight, cysteine-rich protein called metallothionein …

Metallothionein: an intracellular protein to protect against cadmium toxicity

CD Klaassen, J Liu, S Choudhuri - Annual review of …, 1999 - annualreviews.org
▪ Abstract Metallothioneins (MT) are low-molecular-weight, cysteine-rich, metal-binding
proteins. MT genes are readily induced by various physiologic and toxicologic stimuli …

The chronic toxicity of aluminium, cadmium, mercury, and lead in birds: a review

AM Scheuhammer - Environmental Pollution, 1987 - Elsevier
The toxicity of chronic dietary metal exposure in birds is reviewed. It is concluded that
significant physiological and biochemical responses to such exposure conditions occur at …

Historical perspectives on cadmium toxicology

GF Nordberg - Toxicology and applied pharmacology, 2009 - Elsevier
The first health effects of cadmium (Cd) were reported already in 1858. Respiratory and
gastrointestinal symptoms occurred among persons using Cd-containing polishing agent …

Molecular and ionic mimicry and the transport of toxic metals

CC Bridges, RK Zalups - Toxicology and applied pharmacology, 2005 - Elsevier
Despite many scientific advances, human exposure to, and intoxication by, toxic metal
species continues to occur. Surprisingly, little is understood about the mechanisms by which …

Molecular handling of cadmium in transporting epithelia

RK Zalups, S Ahmad - Toxicology and applied pharmacology, 2003 - Elsevier
Cadmium (Cd) is an industrial and environmental pollutant that affects adversely a number
of organs in humans and other mammals, including the kidneys, liver, lungs, pancreas …