The complement membrane attack complex (MAC) is classically known as a cytolytic effector
of innate and adaptive immunity that forms pores in the plasma membrane of pathogens or …

Purpose: Familial Mediterranean fever (FMF) is the most common monogenic auto-
inflammatory disease characterized by recurrent attacks of fever and serositis. It is …

Familial Mediterranean fever (FMF) is a hereditary auto-inflammatory disease, characterised
by recurrent episodes of fever and serositis. Since 1972, colchicine has been the drug of …

ABSTRACT Introduction Familial Mediterranean Fever (FMF) is the most common
autoinflammatory disease that has mainly been treated with colchicine since 1972. A …

Rationale & Objective Outcomes of kidney transplantation for patients with renal AA
amyloidosis are uncertain, with reports of poor survival and high rates of disease recurrence …

Abstract Familial Mediterranean Fever (FMF) is the most prevalent genetic autoinflammatory
disorder. In most patients, treatment with colchicine can prevent attacks of fever and …

Objective To evaluate the safety of canakinumab using real-world data in patients with
systemic juvenile idiopathic arthritis (sJIA) and autoinflammatory diseases (AID). Research …

The kidney represents an important target of systemic inflammation. Its involvement in
monogenic and multifactorial autoinflammatory diseases (AIDs) vary from peculiar and …

Background The efficacy of anti‐interleukin‐1 (IL‐1) drugs in kidney transplant patients with
FMF‐AA who developed colchicine resistance has not been clearly demonstrated. Method …

As the inflammation research improves year-by-year, so does our understanding of the
autoinflammatory conditions. Over the past years, the number of monogenic …