RNA and DNA molecules can form complex, three-dimensional folded structures that have
surprisingly sophisticated functions, including catalysing chemical reactions and controlling …

Use of the zebrafish as a model of vertebrate development and disease has expanded
dramatically over the past decade. While many articles have discussed the strengths of …

RNase P is a ribozyme originally identified for its role in maturation of tRNAs by cleavage of
precursor tRNAs (pre‐tRNAs) at the 5′‐end termini. RNase P is a ribonucleoprotein …

Last December marked the 20th anniversary of the Nobel Prize in Chemistry to Sidney
Altman and Thomas Cech for their discovery of RNA catalysts in bacterial ribonuclease P …

Future soybean [Glycine max (L.) Merr.] cultivars with elevated or reduced concentrations of
isoflavones may be required to satisfy the food market. Climate influences isoflavone …

The RNA cleavage activity of RNase P can be employed to decrease the levels of specific
RNAs and to study their function or even to eradicate pathogens. Two different technologies …

Suppression subtractive hybridization (SSH) was employed to identify lettuce (Lactuca
sativa) genes that are differentially expressed in symptomatic leaves infected with …

Respiratory diseases provide an attractive target for gene silencing using small nucleic
acids since the respiratory epithelium can be reached by inhalation therapy. Natural …

External guide sequence (EGS) technique, a branch of ribozyme strategy, can be enticed to
cleave the target mRNA by forming a tRNA-like structure. In the present study, no tail gene …

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