Asthma is a complex chronic inflammatory disease of the airways that involves the activation
of many inflammatory and structural cells, all of which release inflammatory mediators that …

Immunological activation of mast cells is an important trigger in the cascade of inflammatory
events leading to the manifestation of allergic diseases. Pharmacological studies using the …

The term exercise-induced bronchospasm (EIB) describes the acute transient airway
narrowing that occurs during and most often after exercise in 10 to 50% of elite athletes …

Bronchial hyperresponsiveness (BHR), an abnormal increase in airflow limitation following
the exposure to a stimulus, is an important pathophysiological characteristic of bronchial …

Publisher Summary This chapter discusses the recent developments in research on the
pathobiology of the disease. The focus is on the cellular mechanisms of the disease as …

Exercise‐induced bronchoconstriction (EIB) is exaggerated constriction of the airways
usually soon after cessation of exercise. This is most often a response to airway dehydration …

Asthma is now thought to be a chronic inflammatory disease of the airways. The roles of
prostanoids, thromboxane A2 (TXA2) and the prostaglandins (PGs) in the pathogenesis and …

Exercise-induced asthma (EIA) refers to the transient narrowing of the airways that occurs
after vigorous exercise in 50–60% of patients with asthma. The need to condition the air …

These studies were undertaken to determine the potential role of thromboxane receptors
(TP) in bladder cancer. The data reported herein show that expression of the TP-β receptor …

Airflow-induced bronchoconstriction (AIB) in mammals can be broadly categorized as either
vagal-dependent or vagal-independent. Among mammals, rabbits and cats belong to the …