Transporters in the mammary gland—contribution to presence of nutrients and drugs into milk

AM García-Lino, I Álvarez-Fernández… - Nutrients, 2019 - mdpi.com
A large number of nutrients and bioactive ingredients found in milk play an important role in
the nourishment of breast-fed infants and dairy consumers. Some of these ingredients …

[HTML][HTML] Jugular arginine infusion relieves lipopolysaccharide-triggered inflammatory stress and improves immunity status of lactating dairy cows

FF Zhao, TY Wu, HR Wang, LY Ding, G Ahmed… - Journal of dairy …, 2018 - Elsevier
The objective of this study was to evaluate the effects of jugular l-Arg infusion on
performance and immune function during lipopolysaccharide (LPS)-induced inflammation of …

Human food safety implications of variation in food animal drug metabolism

Z Lin, CI Vahl, JE Riviere - Scientific Reports, 2016 - nature.com
Violative drug residues in animal-derived foods are a global food safety concern. The use of
a fixed main metabolite to parent drug (M/D) ratio determined in healthy animals to establish …

Development of an indirect competitive enzyme-linked immunosorbent assay for detecting flunixin and 5-hydroxyflunixin residues in bovine muscle and milk

X Chen, S Peng, C Liu, X Zou, Y Ke… - Food and agricultural …, 2019 - Taylor & Francis
The flunixin residues in foods of animal origin could pose hazards for human health. In this
paper, a broad-selectivity polyclonal antibody was obtained using 5-hydroxyflunixin coupled …

Evaluation of rapid and standard tandem mass spectrometric methods to analyse veterinary drugs and their metabolites in antemortem bodily fluids from food animals

WL Shelver, S Chakrabarty, JM Young… - Food Additives & …, 2022 - Taylor & Francis
Antemortem bodily fluids can serve as an indicator of veterinary medicine exposure prior to
food animal slaughter. A multi-residue, rapid screen electrospray ionisation mass …

Electrospray ionization rapid screening sans liquid chromatography column: A sensitive method for detection and quantification of chemicals in animal tissues and …

S Chakrabarty, WL Shelver… - Rapid Communications in …, 2020 - Wiley Online Library
Rationale Electrospray ionization mass spectrometry (ESI‐MS) in conjunction with liquid
chromatography (LC) can provide accurate quantitative data, but it is not well‐suited for the …

Role of ABCG2 in secretion into milk of the anti-inflammatory flunixin and its main metabolite: in vitro-in vivo correlation in mice and cows

D Garcia-Mateos, AM Garcia-Lino… - Drug Metabolism and …, 2019 - ASPET
Flunixin meglumine is a nonsteroidal anti-inflammatory drug (NSAID) widely used in
veterinary medicine. It is indicated to treat inflammatory processes, pain, and pyrexia in farm …

Guide to FARAD resources: Historical and future perspectives

JE Riviere, LA Tell, RE Baynes… - Journal of the …, 2017 - Am Vet Med Assoc
1132 JAVMA• Vol 250• No. 10• May 15, 2017 quired both professional judgement and
access to data from the public domain (eg, peer-reviewed literature, conference abstracts …

Development of an immunochromatographic assay for the β-adrenergic agonist feed additive zilpaterol

WL Shelver, DJ Smith - Food Additives & Contaminants: Part A, 2018 - Taylor & Francis
Zilpaterol is a β-adrenergic agonist feed additive approved in the United States to increase
weight gain and improve feed efficiency of cattle. A zilpaterol immunochromatographic …

Avoiding violative flunixin meglumine residues in cattle and swine

PK Sidhu, R Gehring, DA Mzyk… - Journal of the …, 2017 - Am Vet Med Assoc
JAVMA• Vol 250• No. 2• January 15, 2017 183 cally, the WDT is the point following
administration of the labeled dosage of a drug after which there is 95% confidence that 99 …