Zinc, present in all forms of life, is an essential element for humans. It is one of the most
abundant metals in our body. Because of its importance, any malfunctions of its homeostasis …

Interactions between the nervous system and immune system have been studied
extensively. However, the mechanisms underlying the neural regulation of immune activity …

We have synthesized and evaluated a series of hydroxymethyl rhodamine derivatives and
found an intriguing difference of intramolecular spirocyclization behavior: the acetylated …

Inflammation is implicated in cancer genesis and invasiveness and is frequently associated
with a poor prognosis in cancer patients; thus, it becomes a focus of oncology research on …

Hypertension, which often exists as a comorbid condition in cancer patients, is considered
as a factor affecting cancer progression. The renin-angiotensin system (RAS) plays an …

Leucine aminopeptidases (LAPs) were associated with tumor cell proliferation, invasion
and/or angiogenesis. LAP3 is one important member of this family. However, its clinical …

Activity based photosensitizers (PS) continue to attract great attention as they enable
selective photodynamic therapy action on cancer cells while sparing normal cells even …

Leucine aminopeptidases (LAPs) were associated with tumor cell proliferation, invasion
and/or angiogenesis. We aimed to examine the biological function of LAP3 in esophageal …

Abstract Leucine aminopeptidase 3 (LAP3), belonging to the M1 family, has been proved to
catalyze the hydrolysis of leucine residues. Leucine aminopeptidases are involved in many …

Diabetic nephropathy (DN) is one of the most serious and general complications of diabetes,
while schedules for prevention and treatment are unsatisfactory. Leucine aminopeptidase …