I'm coming to GEF you: Regulation of RhoGEFs during cell migration
SM Goicoechea, S Awadia… - Cell adhesion & …, 2014 - Taylor & Francis
Cell migration is a highly regulated multistep process that requires the coordinated
regulation of cell adhesion, protrusion, and contraction. These processes require numerous …
regulation of cell adhesion, protrusion, and contraction. These processes require numerous …
RHOA in gastric cancer: functional roles and therapeutic potential
S Nam, JH Kim, DH Lee - Frontiers in genetics, 2019 - frontiersin.org
The well-known signal mediator and small GTPase family member, RHOA, has now been
associated with the progression of specific malignancies. In this review, we appraise the …
associated with the progression of specific malignancies. In this review, we appraise the …
Can anesthetic technique for primary breast cancer surgery affect recurrence or metastasis?
AK Exadaktylos, DJ Buggy, DC Moriarty… - …, 2006 - pmc.ncbi.nlm.nih.gov
Background: Regional anesthesia is known to prevent or attenuate the surgical stress
response; thus, inhibiting surgical stress by paravertebral anesthesia might attenuate …
response; thus, inhibiting surgical stress by paravertebral anesthesia might attenuate …
[HTML][HTML] Divergent transcription: a driving force for new gene origination?
X Wu, PA Sharp - Cell, 2013 - cell.com
The mammalian genome is extensively transcribed, a large fraction of which is divergent
transcription from promoters and enhancers that is tightly coupled with active gene …
transcription from promoters and enhancers that is tightly coupled with active gene …
AAV-Net1 facilitates the trans-differentiation of supporting cells into hair cells in the murine cochlea
L Zhang, Y Fang, F Tan, F Guo, Z Zhang, N Li… - Cellular and Molecular …, 2023 - Springer
Mechanosensitive hair cells (HCs) in the cochlear sensory epithelium are critical for sound
detection and transduction. Mammalian HCs in the cochlea undergo cytogenesis during …
detection and transduction. Mammalian HCs in the cochlea undergo cytogenesis during …
Direct effect of morphine on breast cancer cell function in vitro: role of the NET1 gene
Background Experimental data suggest that postoperative analgesia in general and opioids
in particular may affect the risk of metastases after primary cancer surgery. Perioperative …
in particular may affect the risk of metastases after primary cancer surgery. Perioperative …
Propofol and bupivacaine in breast cancer cell function in vitro–role of the NET1 gene
Background: It has been hypothesized that anaesthesia during primary breast cancer
surgery may influence recurrence or metastasis. Effects of anaesthetic drugs on breast …
surgery may influence recurrence or metastasis. Effects of anaesthetic drugs on breast …
MYEOV increases HES1 expression and promotes pancreatic cancer progression by enhancing SOX9 transactivity
E Liang, Y Lu, Y Shi, Q Zhou, F Zhi - Oncogene, 2020 - nature.com
Emerging evidence indicates that myeloma overexpressed (MYEOV) is an oncogene and
plays crucial roles in multiple human cancers. However, its roles in the development of …
plays crucial roles in multiple human cancers. However, its roles in the development of …
NET1-mediated RhoA activation facilitates lysophosphatidic acid-induced cell migration and invasion in gastric cancer
The most lethal aspects of gastric adenocarcinoma (GA) are its invasive and metastatic
properties. This aggressive phenotype remains poorly understood. We have recently …
properties. This aggressive phenotype remains poorly understood. We have recently …
MYEOV functions as an amplified competing endogenous RNA in promoting metastasis by activating TGF-β pathway in NSCLC
Non-small cell lung cancer (NSCLC) remains a major cause of death worldwide. As
metastatic disease is primarily responsible for the poor clinical outcome of NSCLC, it is …
metastatic disease is primarily responsible for the poor clinical outcome of NSCLC, it is …