Role of omega-3 fatty acids in cardiovascular disease: the debate continues

SCR Sherratt, P Libby, MJ Budoff, DL Bhatt… - Current atherosclerosis …, 2023 - Springer
Abstract Purpose of Review The omega-3 fatty acids (n3-FAs), eicosapentaenoic acid (EPA)
and docosahexaenoic acid (DHA), have recently undergone testing for their ability to reduce …

The dawn of a new era of targeted lipid-lowering therapies

L Tokgözoğlu, P Libby - European heart journal, 2022 - academic.oup.com
Lipid risk factors for cardiovascular disease depend in part on lifestyle, but optimum control
of lipids often demands additional measures. Low-density lipoprotein (LDL) doubtless …

Effect of icosapent ethyl on progression of coronary atherosclerosis in patients with elevated triglycerides on statin therapy: final results of the EVAPORATE trial

MJ Budoff, DL Bhatt, A Kinninger… - European Heart …, 2020 - academic.oup.com
Aims Despite the effects of statins in reducing cardiovascular events and slowing
progression of coronary atherosclerosis, significant cardiovascular (CV) risk remains …

Mineral oil: safety and use as placebo in REDUCE-IT and other clinical studies

B Olshansky, MK Chung, MJ Budoff… - European Heart …, 2020 - academic.oup.com
Mineral oil is often used as a clinical trial placebo. Pharmaceutical-grade mineral oil consists
of a mixture of saturated hydrocarbons, with a purity and chemical structure that differs …

Lipid lowering drugs: present status and future developments

M Ruscica, N Ferri, RD Santos, CR Sirtori… - Current Atherosclerosis …, 2021 - Springer
Purpose of review Based on the recent data of the DA VINCI study, it is clear that, besides
utilization of statins, there is a need to increase non-statin lipid lowering approaches to …

Quantitative assessment of atherosclerotic plaque, recent progress and current limitations

MC Williams, JP Earls, H Hecht - Journal of Cardiovascular Computed …, 2022 - Elsevier
An important advantage of computed tomography coronary angiography (CCTA) is its ability
to visualize the presence and severity of atherosclerotic plaque, rather than just assessing …

Do patients benefit from omega-3 fatty acids?

SCR Sherratt, RP Mason, P Libby… - Cardiovascular …, 2023 - academic.oup.com
Abstract Omega-3 fatty acids (O3FAs) possess beneficial properties for cardiovascular (CV)
health and elevated O3FA levels are associated with lower incident risk for CV disease …

Omega-3 fatty acids in cardiovascular disease and diabetes: a review of recent evidence

S Bhat, S Sarkar, D Zaffar, P Dandona… - Current Cardiology …, 2023 - Springer
Abstract Purpose of Review Omega-3 fatty acids (n-3 FA) lower triglycerides, have anti-
inflammatory properties, and improve metabolism. Clinical evidence of cardiovascular …

[HTML][HTML] A biological rationale for the disparate effects of omega-3 fatty acids on cardiovascular disease outcomes

SCR Sherratt, P Libby, DL Bhatt, RP Mason - … , Leukotrienes and Essential …, 2022 - Elsevier
The omega-3 fatty acids (n3-FAs) eicosapentaenoic acid (EPA) and docosahexaenoic acid
(DHA) rapidly incorporate into cell membranes where they modulate signal transduction …

Atherosclerotic plaque stabilization and regression: a review of clinical evidence

A Sarraju, SE Nissen - Nature Reviews Cardiology, 2024 - nature.com
Atherosclerotic plaque results from a complex interplay between lipid deposition,
inflammatory changes, cell migration and arterial wall injury. Over the past two decades …