Botulism

J Sobel - Beyond anthrax: the weaponization of infectious …, 2009 - Springer
In the early 1960s, as part of the German biowarfare program [1], laboratory workers
exposed rabbits and guinea pigs to aerosolized botulinum toxin type A. The animals were …

Diffusion, spread, and migration of botulinum toxin

J Ramirez‐Castaneda, J Jankovic… - Movement …, 2013 - Wiley Online Library
Botulinum toxin (BoNT) is an acetylcholine release inhibitor and a neuromuscular blocking
agent used for the treatment of a variety of neurologic and medical conditions. The efficacy …

Botulinum toxin

PK Nigam, A Nigam - Indian journal of dermatology, 2010 - journals.lww.com
Botulinum toxin, one of the most poisonous biological substances known, is a neurotoxin
produced by the bacterium Clostridium botulinum. C. botulinum elaborates eight …

Botulinum toxin assessment, intervention and after‐care for lower limb spasticity in children with cerebral palsy: international consensus statement

SC Love, I Novak, M Kentish… - European journal of …, 2010 - Wiley Online Library
Botulinum neurotoxin type‐A (BoNT‐A) has been used in association with other
interventions in the management of spasticity in children with cerebral palsy (CP) for almost …

The expanding therapeutic utility of botulinum neurotoxins

E Fonfria, J Maignel, S Lezmi, V Martin, A Splevins… - Toxins, 2018 - mdpi.com
Botulinum neurotoxin (BoNT) is a major therapeutic agent that is licensed in neurological
indications, such as dystonia and spasticity. The BoNT family, which is produced in nature …

Uses of botulinum toxin injection in medicine today

A Münchau, KP Bhatia - Bmj, 2000 - bmj.com
Uses of botulinum toxin injection in medicine today | The BMJ Skip to main content Intended
for healthcare professionals Access provided by Google Indexer Subscribe My Account My …

Serious and long-term adverse events associated with the therapeutic and cosmetic use of botulinum toxin

E Yiannakopoulou - Pharmacology, 2015 - karger.com
Although botulinum toxin is generally considered safe, its widespread use and the
constantly expanded indications raise safety issues. This study aimed to review the serious …

Complications and adverse reactions with the use of botulinum toxin

AW Klein - Disease-A-Month, 2002 - Elsevier
Botulinum toxins are the causative agents of the severe food-borne illness botulism. With
lethal doses approximating 10− 9 g/kg body weight, these neurotoxins represent some of the …

Botulism

EA Johnson, C Montecucco - Handbook of clinical neurology, 2008 - Elsevier
Publisher Summary Botulism is an acute neuroparalytic disease of humans and animals
caused through the action of botulinum neurotoxins (BoNTs) acting at the neuromuscular …

Contraindications and complications with the use of botulinum toxin

AW Klein - Clinics in dermatology, 2004 - Elsevier
Cosmetic use of BTX has skyrocketed in recent years, especially since the approval of BTX-
A for treatment of glabellar lines. Complications and adverse reactions can easily arise …