Overview of animal models of attention deficit hyperactivity disorder (ADHD)

VA Russell - Current protocols in neuroscience, 2011 - Wiley Online Library
Attention‐deficit/hyperactivity disorder (ADHD) is a heterogeneous, highly heritable,
behavioral disorder that affects∼ 5% to 10% of children worldwide. Although animal models …

Neurobiology of animal models of attention-deficit hyperactivity disorder

VA Russell - Journal of neuroscience methods, 2007 - Elsevier
Attention-deficit hyperactivity disorder (ADHD) is a heterogeneous, highly heritable, disorder
resulting from complex gene–gene and gene–environment interactions. The defining …

[HTML][HTML] Cannabidiol exhibits anxiolytic but not antipsychotic property evaluated in the social interaction test

V Almeida, R Levin, FF Peres, ST Niigaki… - Progress in Neuro …, 2013 - Elsevier
Cannabidiol (CBD), a non-psychotomimetic compound of the Cannabis sativa, has been
reported to have central therapeutic actions, such as antipsychotic and anxiolytic effects. We …

Paradoxical sleep deprivation impairs acquisition, consolidation, and retrieval of a discriminative avoidance task in rats

TA Alvarenga, CL Patti, ML Andersen, RH Silva… - Neurobiology of learning …, 2008 - Elsevier
The aim of the present study was to investigate the effects of paradoxical sleep deprivation
(PSD) for 96h on the learning/memory processes in rats submitted to the plus-maze …

Neuroleptic drugs revert the contextual fear conditioning deficit presented by spontaneously hypertensive rats: a potential animal model of emotional context …

MB Calzavara, WA Medrano, R Levin… - Schizophrenia …, 2009 - academic.oup.com
Schizophrenia, bipolar disorder, and attention deficit/hyperactivity disorder (ADHD) present
abnormalities in emotion processing. A previous study showed that the spontaneously …

Chronic perfusion of angiotensin II causes cognitive dysfunctions and anxiety in mice

S Duchemin, E Belanger, R Wu, G Ferland… - Physiology & …, 2013 - Elsevier
High blood pressure is a major risk factor in the onset of cerebrovascular diseases and
cognitive impairment. However, mechanisms by which these occur remain unclear and …

Blood–brain barrier leakage and perivascular collagen accumulation precede microvessel rarefaction and memory impairment in a chronic hypertension animal …

E Özkan, Y Çetin-Taş, E Şekerdağ, AB Kızılırmak… - Metabolic Brain …, 2021 - Springer
Hypertension (HT) is one of the main causes of vascular dementia, lead to cognitive decline.
Here, we investigated the relationship between cerebral microvessels, pericytes …

[HTML][HTML] Spontaneously hypertensive rats manifest deficits in emotional response to 22-kHz and 50-kHz ultrasonic playback

KH Olszyński, R Polowy, AD Wardak… - Progress in Neuro …, 2023 - Elsevier
Many symptoms used routinely for human psychiatric diagnosis cannot be directly observed
in animals which cannot describe their internal states. However, the ultrasonic vocalizations …

Effects of antipsychotics and amphetamine on social behaviors in spontaneously hypertensive rats

MB Calzavara, R Levin, WA Medrano, V Almeida… - Behavioural brain …, 2011 - Elsevier
We have recently reported that spontaneously hypertensive rats (SHRs) exhibit a deficit in
contextual fear conditioning that is specifically reversed by antipsychotic and potentiated by …

Treatment with melatonin after status epilepticus attenuates seizure activity and neuronal damage but does not prevent the disturbance in diurnal rhythms and …

Z Petkova, J Tchekalarova, D Pechlivanova… - Epilepsy & Behavior, 2014 - Elsevier
Melatonin is involved in the control of circadian and seasonal rhythmicity, possesses potent
antioxidant activity, and exerts a neuroprotective and anticonvulsant effect. Spontaneously …