Physical activity has been known as an essential element to promote human health for
centuries. Thus, exercise intervention is encouraged to battle against sedentary lifestyle …

Peripheral nerves exist in a stable state in adulthood providing a rapid bidirectional
signaling system to control tissue structure and function. However, following injury …

Regeneration is a heroic biological process that restores tissue architecture and function in
the face of day-to-day cell loss or the aftershock of injury. Capacities and mechanisms for …

Abstract Purpose of Review This review examines the diverse functional relationships that
exist between the peripheral nervous system (PNS) and bone, including key advances over …

Deer antlers are the only known mammalian organ that, once lost, can fully grow back
naturally. Hence, the antler offers a unique opportunity to learn how nature has solved the …

One of the enduring debates in regeneration biology is the degree to which regeneration
mirrors development. Recent technical advances, such as single-cell transcriptomics and …

Understanding the remarkable capacity of vertebrates to naturally regenerate injured body
parts has great importance for potential translation into human therapeutic applications. As …

Humans and mice have the ability to regenerate the distal digit tip, the terminal phalanx (P3)
in response to amputation. What distinguishes P3 regeneration from regenerative failure is …

Trisomy of human chromosome 21 (Ts21) individuals present with a spectrum of low bone
mineral density (BMD) that predisposes this vulnerable group to skeletal injuries. To …

In response to injury, humans and many other mammals form a fibrous scar that lacks the
structure and function of the original tissue, whereas other vertebrate species can …