[HTML][HTML] Autophagy during viral infection—a double-edged sword
Autophagy is a powerful tool that host cells use to defend against viral infection. Double-
membrane vesicles, termed autophagosomes, deliver trapped viral cargo to the lysosome …
membrane vesicles, termed autophagosomes, deliver trapped viral cargo to the lysosome …
A comprehensive review of autophagy and its various roles in infectious, non-infectious, and lifestyle diseases: current knowledge and prospects for disease …
Autophagy (self-eating) is a conserved cellular degradation process that plays important
roles in maintaining homeostasis and preventing nutritional, metabolic, and infection …
roles in maintaining homeostasis and preventing nutritional, metabolic, and infection …
Parkinson's disease-related proteins PINK1 and Parkin repress mitochondrial antigen presentation
D Matheoud, A Sugiura, A Bellemare-Pelletier… - Cell, 2016 - cell.com
Antigen presentation is essential for establishing immune tolerance and for immune
responses against infectious disease and cancer. Although antigen presentation can be …
responses against infectious disease and cancer. Although antigen presentation can be …
Autophagy and autophagy-related proteins in the immune system
ST Shibutani, T Saitoh, H Nowag, C Münz… - Nature …, 2015 - nature.com
Autophagy is an intracellular bulk degradation system that is highly conserved in
eukaryotes. The discovery of autophagy-related ('ATG') proteins in the 1990s greatly …
eukaryotes. The discovery of autophagy-related ('ATG') proteins in the 1990s greatly …
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …
Since then, this topic has received increasing attention, and many scientists have entered …
Interferon-independent STING signaling promotes resistance to HSV-1 in vivo
LH Yamashiro, SC Wilson, HM Morrison… - Nature …, 2020 - nature.com
Abstract The Stimulator of Interferon Genes (STING) pathway initiates potent immune
responses upon recognition of DNA. To initiate signaling, serine 365 (S365) in the C …
responses upon recognition of DNA. To initiate signaling, serine 365 (S365) in the C …
PAMP s and DAMP s: Signal 0s that spur autophagy and immunity
Pathogen‐associated molecular pattern molecules (PAMP s) are derived from
microorganisms and recognized by pattern recognition receptor (PRR)‐bearing cells of the …
microorganisms and recognized by pattern recognition receptor (PRR)‐bearing cells of the …
Autophagy modulation as a potential therapeutic target for diverse diseases
Autophagy is an essential, conserved lysosomal degradation pathway that controls the
quality of the cytoplasm by eliminating protein aggregates and damaged organelles. It …
quality of the cytoplasm by eliminating protein aggregates and damaged organelles. It …
Autophagy in immunity and inflammation
Autophagy is an essential, homeostatic process by which cells break down their own
components. Perhaps the most primordial function of this lysosomal degradation pathway is …
components. Perhaps the most primordial function of this lysosomal degradation pathway is …
The role of Atg proteins in autophagosome formation
N Mizushima, T Yoshimori… - Annual review of cell and …, 2011 - annualreviews.org
Macroautophagy is mediated by a unique organelle, the autophagosome, which encloses a
portion of cytoplasm for delivery to the lysosome. Autophagosome formation is dynamically …
portion of cytoplasm for delivery to the lysosome. Autophagosome formation is dynamically …