Prosthetic joint infection (PJI) is a severe complication after arthroplasty. Its management
combines surgical intervention, whose type depends on the clinical situation, and prolonged …

Over the last several decades, periprosthetic joint infection has been increasing in incidence
and is occurring in more complex patients. While there have been advances in both surgical …

The treatment of staphylococcal prosthetic joint infection (PJI) with debridement, antibiotics,
and retention of the implant (DAIR) often results in failure. An important evidence gap …

Abstract Purpose of Review Antimicrobial stewardship within acute care is common and has
been expanding to outpatient areas. Some inpatient antimicrobial stewardship tactics apply …

Objectives This study aimed at characterizing the pharmacokinetics (PK) of oral levofloxacin
in adult patients in order to optimize dosing scheme and explore the PK/pharmacodynamics …

Objectives: To define outpatient parenteral antimicrobial therapy (OPAT) clinical pharmacy
practice across the United States, specifically pharmacist functions, design of pharmacist …

Whether rifampin benefits retained staphylococcal prosthetic joint infection is unsettled. In a
meta-analysis of 8 studies, we found greater clinical cure with fluoroquinolone-rifampin vs all …

Fluoroquinolones (FQs) are considered the most effective antimicrobial treatment for Gram-
negative prosthetic joint infection (GN-PJI). Alternatives are needed due to increasing FQ …

Salmonella Thompson is a prevalent foodborne pathogen and a major threat to food safety
and public health. This study aims to reveal the dissemination mechanism of S. Thompson …

Background The optimal duration of antibiotic therapy after debridement and implant
retention (DAIR) for periprosthetic joint infections (PJIs) is debated. Furthermore, the best …