One early phase of atherosclerosis involves the recruitment of inflammatory cells from the
circulation and their transendothelial migration. This process is predominantly mediated by …

The pathogenesis of arterial thrombotic disease involves multiple genetic and environmental
factors related to atherosclerosis and thrombosis. Acute thrombosis at the site of a ruptured …

Membrane glycoprotein IIb/IIIa plays a major role in platelet function. The gene encoding the
glycoprotein IIIa shows a common polymorphism Pl A1/Pl A2 that was variably associated …

A number of molecules on the surface of red blood cells (RBCs) and platelets express
antigenic activity. Various biochemical and molecular approaches have been used to …

The polymorphism responsible for the PlA2 alloantigen on the β3-component of β3-
containing integrins is reported to be a risk factor for coronary thrombosis. This study …

Background The PlA2 polymorphism of glycoprotein IIIa (GPIIIa) has been previously
identified as being associated with myocardial infarction (MI), but whether this represents a …

Background: The pathogenesis of thrombosis in childhood seems to be multifactorial
implicating genetic and environmental factors. Aim: To compare the distributions of …

Изучение молекулярно-биологических аспектов функционирования как клетки, так и
систем организма человека привело к открытию новых ингибиторов каскада …

Acute myocardial infarction still represents the major cause of mortality in high-income
countries. Therefore, considerable efforts have been focused on the treatment of myocardial …

BACKGROUND: Genetic polymorphisms may affect the balance between coagulation and
fibrinolysis and thereby affect individual vulnerability to acute myocardial infarction (MI) …