[HTML][HTML] Anandamide and other N-acylethanolamines: A class of signaling lipids with therapeutic opportunities

ED Mock, B Gagestein, M van der Stelt - Progress in Lipid Research, 2023 - Elsevier
Abstract N-acylethanolamines (NAEs), including N-palmitoylethanolamine (PEA), N-
oleoylethanolamine (OEA), N-arachidonoylethanolamine (AEA, anandamide), N …

Functional roles of fatty acids and their effects on human health

PC Calder - Journal of parenteral and enteral nutrition, 2015 - Wiley Online Library
A variety of fatty acids exists in the diet of humans, in the bloodstream of humans, and in
cells and tissues of humans. Fatty acids are energy sources and membrane constituents …

The CB2 receptor and its role as a regulator of inflammation

C Turcotte, MR Blanchet, M Laviolette… - Cellular and Molecular …, 2016 - Springer
The CB 2 receptor is the peripheral receptor for cannabinoids. It is mainly expressed in
immune tissues, highlighting the possibility that the endocannabinoid system has an …

Bioactive lipids, inflammation and chronic diseases

A Leuti, D Fazio, M Fava, A Piccoli, S Oddi… - Advanced Drug Delivery …, 2020 - Elsevier
Endogenous bioactive lipids are part of a complex network that modulates a plethora of
cellular and molecular processes involved in health and disease, of which inflammation …

Endocannabinoids—at the crossroads between the gut microbiota and host metabolism

PD Cani, H Plovier, M Van Hul, L Geurts… - Nature Reviews …, 2016 - nature.com
Various metabolic disorders are associated with changes in inflammatory tone. Among the
latest advances in the metabolism field, the discovery that gut microorganisms have a major …

Protective Effects of (E)-β-Caryophyllene (BCP) in Chronic Inflammation

R Scandiffio, F Geddo, E Cottone, G Querio… - Nutrients, 2020 - mdpi.com
(E)-β-caryophyllene (BCP) is a bicyclic sesquiterpene widely distributed in the plant
kingdom, where it contributes a unique aroma to essential oils and has a pivotal role in the …

Targeting the endocannabinoid system: future therapeutic strategies

O Aizpurua-Olaizola, I Elezgarai, I Rico-Barrio… - Drug discovery today, 2017 - Elsevier
Highlights•Increased emphasis in recent years on drugs targeting the endocannabinoid
system.•Recent discoveries about the role of the endocannabinoid system are …

Cannabidiol and other non-psychoactive cannabinoids for prevention and treatment of gastrointestinal disorders: useful nutraceuticals?

V Martínez, A Iriondo De-Hond, F Borrelli… - International Journal of …, 2020 - mdpi.com
Cannabis sativa is an aromatic annual flowering plant with several botanical varieties, used
for different purposes, like the production of fibers, the production of oil from the seeds, and …

Production, distribution, and abundance of long-chain omega-3 polyunsaturated fatty acids: a fundamental dichotomy between freshwater and terrestrial ecosystems

SM Hixson, B Sharma, MJ Kainz… - Environmental …, 2015 - cdnsciencepub.com
Long-chain polyunsaturated fatty acids (LC-PUFA) are critical for the health of aquatic and
terrestrial organisms; therefore, understanding the production, distribution, and abundance …

Targeting gut dysbiosis against inflammation and impaired autophagy in Duchenne muscular dystrophy

H Kalkan, E Pagano, D Paris, E Panza… - EMBO Molecular …, 2023 - embopress.org
Nothing is known about the potential implication of gut microbiota in skeletal muscle
disorders. Here, we provide evidence that fecal microbiota composition along with …