Rheumatoid factors: what's new?

OMR Westwood, PN Nelson, FC Hay - Rheumatology, 2006 - academic.oup.com
Rheumatoid arthritis (RA) is a classic example of an autoimmune disorder, with chronic
inflammation of the synovial membrane, and deterioration of cartilage and bone in the …

IgM and its receptors: structural and functional aspects

VB Klimovich - Biochemistry (Moscow), 2011 - Springer
This review combines the data obtained before the beginning of the 1990s with results
published during the last two decades. The predominant form of the IgM molecule is a …

The human IgM pentamer is a mushroom-shaped molecule with a flexural bias

DM Czajkowsky, Z Shao - Proceedings of the National …, 2009 - National Acad Sciences
The textbook planar model of pentameric IgM, a potent activator of complement C1q, is
based upon the crystallographic structure of IgG. Although widely accepted, key predictions …

Ambiguity assessment of small-angle scattering curves from monodisperse systems

MV Petoukhov, DI Svergun - Acta Crystallographica Section D …, 2015 - journals.iucr.org
A novel approach is presented for an a priori assessment of the ambiguity associated with
spherically averaged single-particle scattering. The approach is of broad interest to the …

Intermolecular interactions of IgG1 monoclonal antibodies at high concentrations characterized by light scattering

TM Scherer, J Liu, SJ Shire… - The journal of physical …, 2010 - ACS Publications
Light scattering intensity measurements of solutions of two purified monoclonal antibodies
were performed over a wide range of concentrations (0.5− 275 mg/mL) and ionic strengths …

Structure and properties of iron oxide nanoparticles encapsulated by phospholipids with poly (ethylene glycol) tails

EV Shtykova, X Huang, N Remmes… - The Journal of …, 2007 - ACS Publications
Iron oxide nanoparticles with diameters of 20.1 and 8.5 nm coated with phospholipids
containing poly (ethylene glycol)(PEG) tails were studied using small-angle X-ray scattering …

Hydrophilic monodisperse magnetic nanoparticles protected by an amphiphilic alternating copolymer

EV Shtykova, X Huang, X Gao, JC Dyke… - The Journal of …, 2008 - ACS Publications
Iron oxide nanoparticles (NPs) with diameters of 16.1, 20.5, and 20.8 nm prepared from iron
oleate precursors were coated with poly (maleic acid-alt-1-octadecene)(PMAcOD). The …

Structural characterization of gephyrin by AFM and SAXS reveals a mixture of compact and extended states

B Sander, G Tria, AV Shkumatov, EY Kim… - … Section D: Biological …, 2013 - journals.iucr.org
Gephyrin is a trimeric protein involved in the final steps of molybdenum-cofactor (Moco)
biosynthesis and in the clustering of inhibitory glycine and GABAA receptors at postsynaptic …

Structural studies of protein arginine methyltransferase 2 reveal its interactions with potential substrates and inhibitors

V Cura, N Marechal, N Troffer‐Charlier… - The FEBS …, 2017 - Wiley Online Library
PRMT 2 is the less‐characterized member of the protein arginine methyltransferase family in
terms of structure, activity, and cellular functions. PRMT 2 is a modular protein containing a …

Metalated Diblock and Triblock Poly(ethylene oxide)-block-poly(4-vinylpyridine) Copolymers:  Understanding of Micelle and Bulk Structure

LM Bronstein, SN Sidorov, V Zhirov… - The Journal of …, 2005 - ACS Publications
The paper provides new insights into the structure of Pt-containing diblock and triblock
copolymers based on poly (ethylene oxide)(PEO) and poly (4-vinylpyridine)(P4VP), using a …