Exploring the anti‐cancer potential of dietary phytochemicals for the patients with breast cancer: a comprehensive review

M Sohel, S Aktar, P Biswas, MA Amin… - Cancer …, 2023 - Wiley Online Library
Background The most common and deadly cancer in female is breast cancer (BC) and new
incidence and deaths related to this cancer are rising. Aims Several issues, that is, high cost …

[HTML][HTML] The bioactivities of sclareol: A mini review

J Zhou, X Xie, H Tang, C Peng, F Peng - Frontiers in Pharmacology, 2022 - frontiersin.org
Sclareol, a diterpene alcohol isolated from the herbal and flavor plant clary sage (Salvia
sclarea L.), is far-famed as the predominant ingredient in the refined oil of Salvia sclarea (L.) …

Terpenoids with special pharmacological significance: A review

R Jaeger, E Cuny - Natural product communications, 2016 - journals.sagepub.com
Terpenoids are a very prominent class of natural compounds produced in diverse genera of
plants, fungi, algae and sponges. They gained significant pharmaceutical value since …

Bioactive phytochemicals from shoots and roots of Salvia species

AR Jassbi, S Zare, O Firuzi, J Xiao - Phytochemistry reviews, 2016 - Springer
The plants of the genus Salvia L. are important medicinal herbs of the Lamiaceae family and
some of them such as S. officinalis (sage), S. miltiorrhiza (red sage, Danshen) and S. sclarea …

Structure, catalysis, and inhibition mechanism of prenyltransferase

HY Chang, TH Cheng, AHJ Wang - IUBMB life, 2021 - Wiley Online Library
Isoprenoids, also known as terpenes or terpenoids, represent a large family of natural
products composed of five‐carbon isopentenyl diphosphate or its isomer dimethylallyl …

[HTML][HTML] Salvia sclarea L. Essential Oil Extract and Its Antioxidative Phytochemical Sclareol Inhibit Oxytocin-Induced Uterine Hypercontraction Dysmenorrhea Model by Inhibiting …

J Wong, YF Chiang, YH Shih, CH Chiu, HY Chen… - Antioxidants, 2020 - mdpi.com
Salvia sclarea essential oil is used as an aromatic therapy for dysmenorrhea. Sclareol—one
of the natural products isolated from S. sclarea—displays anti-inflammatory and antioxidant …

Sclareol exhibits anti-inflammatory activity in both lipopolysaccharide-stimulated macrophages and the λ-carrageenan-induced paw edema model

GJ Huang, CH Pan, CH Wu - Journal of Natural Products, 2012 - ACS Publications
Sclareol (1) is a natural fragrance compound used widely in the cosmetic and food
industries. Lipopolysaccharide (LPS)-stimulated RAW264. 7 macrophages and the λ …

Sclareol induces cell cycle arrest and ROS‐mediated apoptosis and ferroptosis in lung adenocarcinoma cells

B Rah, J Shafarin, M Hamad… - Journal of Biochemical …, 2024 - Wiley Online Library
Sclareol (SC) has shown significant anticancer activity against breast and colon cancers
among others. However, its ability to precipitate similar anticancer effects in lung cancer has …

Enhanced biosynthesis of bioactive abietane diterpenes by overexpressing AtDXS or AtDXR genes in Salvia sclarea hairy roots

M Vaccaro, N Malafronte, M Alfieri… - Plant Cell, Tissue and …, 2014 - Springer
Diterpenoids are important compounds for plant survival and have beneficial properties for
humans. Bioactive abietanic diterpenes are synthesized in roots of Salvia sclarea (eg …

[HTML][HTML] Natural Compounds of Salvia L. Genus and Molecular Mechanism of Their Biological Activity

G Zhumaliyeva, A Zhussupova, GE Zhusupova… - Biomedicines, 2023 - mdpi.com
The study of medicinal plants is important, as they are the natural reserve of potent
biologically active compounds. With wide use in traditional medicine and the inclusion of …