Thyroid cancer is a common endocrine malignancy. There has been exciting progress in
understanding its molecular pathogenesis in recent years, as best exemplified by the …

In recent years, the T1799A B-type Raf kinase (BRAF) mutation in thyroid cancer has
received enthusiastic investigation, and significant progress has been made toward …

Tumor cells have an increased demand for nutrients; this demand is met by increased
availability of nutrients through vasculogenesis and by enhanced cellular entry of nutrients …

RASSF1A (Ras association domain family 1 isoform A) is a recently discovered tumor
suppressor whose inactivation is implicated in the development of many human cancers …

Anaplastic thyroid cancer (ATC) is a rare malignancy. While external beam radiation therapy
has improved locoregional control, the median survival of∼ 4 months has not changed in …

Background: Aberrant activation of the phosphatidylinositol-3 kinase (PI3K)/Akt pathway
plays a fundamental role in thyroid tumorigenesis, particularly in follicular thyroid cancer …

The molecular characterization of poorly and anaplastic thyroid carcinomas has been
greatly improved in the last years following the advent of high throughput technologies …

Nasopharyngeal carcinoma (NPC) is a head and neck cancer rare throughout most of the
world but common in certain geographic areas, such as southern Asia. While environmental …

Established human cancer cell lines are routinely used as experimental models for human
cancers. Their validity for such use is analyzed and discussed, with particular focus on …

Thyroid cancer is the most common malignancy in endocrine system, composed of four
major types; papillary thyroid carcinoma, follicular thyroid carcinoma, anaplastic thyroid …