Multicomponent Petasis reaction for the identification of pyrazine based multi-target directed anti-Alzheimer's agents: In-silico design, synthesis, and characterization

H Madhav, SA Abdel-Rahman, MA Hashmi… - European Journal of …, 2023 - Elsevier
Multi-target directed ligands (MTDLs) have recently attracted significant interest due to their
exceptional effectiveness against multi-factorial Alzheimer's disease. The present work …

Diversity-Oriented Repurposing of Pyrimidin-4-yl) oxy) methyl)-1H-1, 2, 3-triazol-1-yl) benzenesulfonamides as Promising Antifungals that inhibit Ergosterol …

H Madhav, S Ahmedi, S Manzoor, V Yadav, AT Khan… - papers.ssrn.com
Mortality and morbidity rates are rising globally in transplant surgery patients due to drug-
resistant fungi, toxic antifungal drugs, and a lack of new treatments. Repurposing existing …