Cancer-associated venous thromboembolism

AA Khorana, N Mackman, A Falanga… - Nature reviews Disease …, 2022 - nature.com
Cancer-associated thrombosis (including venous thromboembolism (VTE) and arterial
events) is highly consequential for patients with cancer and is associated with worsened …

Rare molecular subtypes of lung cancer

G Harada, SR Yang, E Cocco, A Drilon - Nature Reviews Clinical …, 2023 - nature.com
Oncogenes that occur in≤ 5% of non-small-cell lung cancers have been defined as 'rare';
nonetheless, this frequency can correspond to a substantial number of patients diagnosed …

Current treatment and future challenges in ROS1-and ALK-rearranged advanced non-small cell lung cancer

J Remon, D Pignataro, S Novello, F Passiglia - Cancer Treatment Reviews, 2021 - Elsevier
Non─ small cell lung cancer (NSCLC) presents different druggable genetic abnormalities,
including ROS1 and ALK rearrangements, which share relevant clinical features and …

Genomic profiling identifies somatic mutations predicting thromboembolic risk in patients with solid tumors

A Dunbar, KL Bolton, SM Devlin… - Blood, The Journal …, 2021 - ashpublications.org
Venous thromboembolism (VTE) associated with cancer (CAT) is a well-described
complication of cancer and a leading cause of death in patients with cancer. The purpose of …

Molecular pathology of non‐small cell carcinoma

Y Yatabe - Histopathology, 2024 - Wiley Online Library
Currently, lung cancer is treated by the highest number of therapeutic options and the
benefits are based on multiple large‐scale sequencing studies, translational research and …

[HTML][HTML] Thromboembolism in ALK+ and ROS1+ NSCLC patients: A systematic review and meta-analysis

VW Zhu, JJ Zhao, Y Gao, NL Syn, SS Zhang, SHI Ou… - Lung Cancer, 2021 - Elsevier
Introduction Increased thromboembolism (TE) has been reported in ALK+ and ROS1+ non-
small cell lung cancer (NSCLC). Materials and Methods Odds ratios (OR) and hazard ratios …

[HTML][HTML] Risk of thromboembolism in patients with ALK‐and EGFR‐mutant lung cancer: A cohort study

J Roopkumar, SK Poudel, L Gervaso, CA Reddy… - Journal of Thrombosis …, 2021 - Elsevier
Introduction Thromboembolism (TE) is common in patients with non‐small cell lung cancer
(NSCLC) and is associated with worse outcomes. Recent advances in the understanding of …

Cancer and thrombosis: new insights to an old problem

O Leiva, R Newcomb, JM Connors… - JMV-Journal de Médecine …, 2020 - Elsevier
Venous thromboembolism (VTE) is a common complication in patients with cancer and
portends a poor prognosis. Our understanding of the underlying pathophysiology of VTE in …

[HTML][HTML] Impact of ALK rearrangement on venous and arterial thrombotic risk in NSCLC

H Al-Samkari, O Leiva, I Dagogo-Jack, A Shaw… - Journal of Thoracic …, 2020 - Elsevier
Introduction Clinical venous thromboembolism (VTE) risk prediction scores, such as the
Khorana Risk Score, perform poorly in NSCLC, possibly because the tumor molecular …

ROS1-rearranged non–small-cell lung cancer is associated with a high rate of venous thromboembolism: analysis from a phase II, prospective, multicenter, two-arms …

R Chiari, B Ricciuti, L Landi, AM Morelli, A Delmonte… - Clinical Lung Cancer, 2020 - Elsevier
Background Patients with cancer are at increased risk for venous thromboembolism (VTE),
and 8% to 15% of patients with advanced non–small-cell lung cancer (NSCLC) experience …