Nrf2 signaling pathway: a potential therapeutic target in combating oxidative stress and neurotoxicity in chemotherapy-induced cognitive impairment
Chemotherapy-induced cognitive impairment (CICI) is one of the major adverse effects of
antineoplastic drugs, which decrease the quality of life in cancer survivors. Extensive …
antineoplastic drugs, which decrease the quality of life in cancer survivors. Extensive …
Senolytic treatment alleviates doxorubicin‐induced chemobrain
V Budamagunta, A Kumar, A Rani… - Aging cell, 2024 - Wiley Online Library
Doxorubicin (Dox), a widely used treatment for cancer, can result in chemotherapy‐induced
cognitive impairments (chemobrain). Chemobrain is associated with inflammation and …
cognitive impairments (chemobrain). Chemobrain is associated with inflammation and …
Antioxidant and anti-inflammatory potential of crocin on the doxorubicin mediated hepatotoxicity in Wistar rats
Doxorubicin (DXR) is widely used in cancer treatment. However, it has not yet been possible
to prevent the side effects of DXR. The aim of this study was to investigate the …
to prevent the side effects of DXR. The aim of this study was to investigate the …
Alpha-Lipoic acid alleviates imidacloprid-induced neuro-behavioral deficits in rats via Nrf2/HO-1 pathway
Imidacloprid (IMI), a widely used pesticide in agriculture and a potential food contaminant,
poses significant health concerns. This study sought to comprehensively evaluate its …
poses significant health concerns. This study sought to comprehensively evaluate its …
Forced Swimming-Induced Depressive-like Behavior and Anxiety Are Reduced by Chlorpheniramine via Suppression of Oxidative and Inflammatory Mediators and …
HS Alamri, R Mufti, DK Sabir, AA Abuderman… - Current Issues in …, 2023 - mdpi.com
The first-generation antihistamine chlorpheniramine (CPA) is believed to have both
anxiolytic and antidepressant properties. The current study sought to assess the …
anxiolytic and antidepressant properties. The current study sought to assess the …