The synthesis of amides is of huge importance in a wide variety of industrial and academic
fields and is of particular significance in the synthesis of pharmaceuticals. Many of the well …

Amides are undeniably some of the most important compounds in Nature and the chemical
industry, being present in biomolecules, materials, pharmaceuticals and many other …

Large-Scale Applications of Amide Coupling Reagents for the Synthesis of Pharmaceuticals |
Organic Process Research & Development ACS ACS Publications C&EN CAS Find my …

Direct amide formation from unactivated carboxylic acids and amines - Chemical
Communications (RSC Publishing) DOI:10.1039/C1CC15210F Royal Society of Chemistry …

The direct mechanochemical amidation of esters by ball milling is described. The
operationally simple procedure requires an ester, an amine, and substoichiometric KOtBu …

B (OCH2CF3) 3, prepared from readily available B2O3 and 2, 2, 2-trifluoroethanol, is as an
effective reagent for the direct amidation of a variety of carboxylic acids with a broad range of …

Chemical reactions for the formation of amide bonds are among the most commonly used
transformations in organic chemistry, yet they are often highly inefficient. A novel protocol for …

The importance of amides as a component of biomolecules and synthetic products motivates
the development of catalytic, direct amidation methods employing free carboxylic acids and …

Metal‐free catalysis: A method for the transamidation of primary amides with primary or
secondary amines provides access to secondary and tertiary amides, by utilizing catalytic …

The amide functionality is a highly important chemical bond, found in a great number of
synthetic products such as pharmaceuticals, polymers and agrochemicals. The focus of this …