Immune surveillance of mucosal surfaces requires the delivery of intact macromolecules and
microorganisms across epithelial barriers to organized mucosal lymphoid tissues. Transport …

Sulfatide is 3-O-sulfogalactosylceramide that is synthesized by two transferases (ceramide
galactosyltransferase and cerebroside sulfotransferase) from ceramide and is specifically …

Due to climate changes, there has been a large expansion of emerging tick-borne zoonotic
viruses, including Heartland bandavirus (HRTV) and Dabie bandavirus (DBV). As etiologic …

The V3 loop of the human immunodeficiency virus (HIV)-1 surface envelope glycoprotein
gp120 is a sphingolipid-binding domain mediating the attachment of HIV-1 to plasma …

Alzheimer, Parkinson and other neurodegenerative diseases involve a series of brain
proteins, referred to as 'amyloidogenic proteins', with exceptional conformational plasticity …

This book provides basic principles of multivalent interactions found in biological systems as
well as an up-to-date and thorough coverage in design concepts, syntheses, and biological …

Abstract θ-Defensins are circular octadecapeptides that contain an internal tridisulfide
ladder. Because retrocyclin-1, an ancestral hominid θ-defensin, can protect human cells in …

CD8+ T-cells are a critical component of the cellular immune response and they play an
important role in the control of viral infection. During HIV infection, CD8+ T-cells are able to …

Sphingolipids are essential components of eukaryotic cells. In this review, we want to
exemplarily illustrate what is known about the interactions of sphingolipids with various …

Ceramide is a lipid messenger at the heart of sphingolipid metabolism. In concert with its
metabolizing enzymes, particularly sphingomyelinases, it has key roles in regulating the …