Mechanical stimuli have fundamental roles in articular cartilage during health and disease.
Chondrocytes respond to the physical properties of the cartilage extracellular matrix (ECM) …

Objective To review the basic scientific status of repair in articular cartilage tissue and to
assess the efficiency of current clinical therapies instigated for the treatment of structural …

The joints of mammals are lined with cartilage, comprised of individual chondrocytes
embedded in a specialized extracellular matrix. Chondrocytes experience a complex …

This second edition of the Bone Mechanics Handbook summarizes the current
understanding of bone mechanics with comprehensive coverage of the histology …

Primary open angle glaucoma is a common eye disease characterized by loss of the axons
of the retinal ganglion cells leading to progressive loss of vision. The site of damage to the …

By binding magnetic nanoparticles to the surface of cells, it is possible to manipulate and
control cell function with an external magnetic field. The technique of activating cells with …

A wide variety of laboratory apparatuses have been devised for mechanical stimulation of
cell and tissue cultures. This article reviews the functional attributes of several dozen …

Damage to and degeneration of articular cartilage is a major health issue in industrialized
nations. Articular cartilage has a particularly limited capacity for auto regeneration. At …

In two interrelated articles, the current revision of the functional matrix hypothesis extends to
a reconsideration of the relative roles of genomic and of epigenetic processes and …

Mechanical forces influence chondrocyte metabolism and are critically important for
maintenance of normal cartilage structure and integrity. In cells of the musculoskeletal …