Background: Increasingly, studies have focused on the relationship between Helicobacter
pylori (H pylori) cytotoxin associated gene A protein (CagA) Glu-Pro-Ile-Tyr-Ala (EPIYA)-D …

Helicobacter pylori is a spiral-shaped Gram-negative bacterium, which has infected more
than half of the human population. Besides its colonisation capability, the genetic diversity of …

Background and Objectives: Helicobacter pylori infection is associated with chronic gastritis,
ulcers, and gastric cancer. The H. pylori Type 4 secretion system (T4SS) translocates the …

Background The pathogenicity of cagA-positive H. pylori strains is associated with the
number and type of repeated sequences named EPIYA located in the C-terminal region of …

Colonization of the human gastric mucosa by H. pylori may cause peptic and duodenal
ulcers (DUs), gastric lymphomas, and gastric cancers. The cagL gene is a component of cag …

Introduction: As a component of the cag T4SS, the cagL gene is involved in the translocation
of CagA into host cells and is essential for the formation of cag PAI-associated pili between …

幽门螺杆菌(Helicobacter pylori, H. pylori) 与慢性胃炎, 消化性溃疡, 胃黏膜相关淋巴样组织淋巴
瘤, 胃癌等疾病密切相关. H. pylori 致病性主要依赖于其鞭毛, 螺旋结构, 脂多糖 …

Helicobacter pylori infection is strongly associated with gastritis, gastroduodenal ulcer
disease and gastric carcinoma. The virulence of H. pylori strains increases with the …

Background: H. pylori infection induce atrophic gastritis (AG) and intestinal metaplasia (IM)
that can lead to gastric cancer (GC). The severity of gastric lesions is related to H. pylori …

Methods: We used the Preferred Reporting Items for Systematic Review and Meta-Analysis
statement for reporting systematic review and meta-analysis of this study in national and …