[HTML][HTML] Exosomes: key players in cancer and potential therapeutic strategy

J Dai, Y Su, S Zhong, L Cong, B Liu, J Yang… - Signal transduction and …, 2020 - nature.com
Exosomes are extracellular vesicles secreted by most eukaryotic cells and participate in
intercellular communication. The components of exosomes, including proteins, DNA, mRNA …

[HTML][HTML] Isolation and characterization of exosomes for cancer research

L Zhu, HT Sun, S Wang, SL Huang, Y Zheng… - Journal of hematology & …, 2020 - Springer
Exosomes are a subset of extracellular vesicles that carry specific combinations of proteins,
nucleic acids, metabolites, and lipids. Mounting evidence suggests that exosomes …

[HTML][HTML] LncRNA KLF3-AS1 in human mesenchymal stem cell-derived exosomes ameliorates pyroptosis of cardiomyocytes and myocardial infarction through miR-138 …

Q Mao, XL Liang, CL Zhang, YH Pang… - Stem cell research & …, 2019 - Springer
Aim Myocardial infarction (MI) is a severe disease with increased mortality and disability
rates, posing heavy economic burden for society. Exosomes were uncovered to mediate …

[HTML][HTML] Comprehensive landscape of extracellular vesicle-derived RNAs in cancer initiation, progression, metastasis and cancer immunology

W Hu, C Liu, ZY Bi, Q Zhou, H Zhang, LL Li, J Zhang… - Molecular cancer, 2020 - Springer
Extracellular vesicles (EVs), a class of heterogeneous membrane vesicles, are generally
divided into exosomes and microvesicles on basis of their origination from the endosomal …

[HTML][HTML] Long non-coding RNAs regulate drug resistance in cancer

K Liu, L Gao, X Ma, JJ Huang, J Chen, L Zeng… - Molecular cancer, 2020 - Springer
Chemoresistance, whether intrinsic or acquired, is a major obstacle in the treatment of
cancer. The resistance of cancer cells to chemotherapeutic drugs can result from various …

[HTML][HTML] Dissecting the single-cell transcriptome network underlying esophagus non-malignant tissues and esophageal squamous cell carcinoma

Z Chen, M Zhao, J Liang, Z Hu, Y Huang, M Li… - …, 2021 - thelancet.com
Background Esophageal squamous cell carcinoma (ESCC) is among the most prevalent
causes of cancer-related death in adults. Tumor microenvironment (TME) has been …

[HTML][HTML] The key roles of cancer stem cell-derived extracellular vesicles

C Su, J Zhang, Y Yarden, L Fu - Signal transduction and targeted …, 2021 - nature.com
Cancer stem cells (CSCs), the subpopulation of cancer cells, have the capability of
proliferation, self-renewal, and differentiation. The presence of CSCs is a key factor leading …

Extracellular vesicles as a novel source of biomarkers in liquid biopsies for monitoring cancer progression and drug resistance

MH Vasconcelos, HR Caires, A Ābols… - Drug Resistance …, 2019 - Elsevier
Cancer-derived extracellular vesicles (EVs) have been detected in the bloodstream and
other biofluids of cancer patients. They carry various tumor-derived molecules such as …

[HTML][HTML] The role of extracellular vesicles in the transfer of drug resistance competences to cancer cells

CPR Xavier, DC Belisario, R Rebelo, YG Assaraf… - Drug Resistance …, 2022 - Elsevier
Drug resistance remains a major hurdle to successful cancer treatment, being accountable
for approximately 90% of cancer-related deaths. In the past years, increasing attention has …

A novel long non‐coding RNA lnc030 maintains breast cancer stem cell stemness by stabilizing SQLE mRNA and increasing cholesterol synthesis

Y Qin, Y Hou, S Liu, P Zhu, X Wan, M Zhao… - Advanced …, 2021 - Wiley Online Library
Cancer stem cells (CSCs) are considered the roots of cancer metastasis and recurrence
(CSCs), due in part to their self‐renewal and therapy resistance properties. However, the …