Neuroendocrine and neuroimmune mechanisms underlying comorbidity of pain and obesity
DH Zhang, YH Fan, YQ Zhang, H Cao - Life Sciences, 2023 - Elsevier
Pain and obesity, as well as their associated impairments, are major health concerns.
Understanding the relationship between the two is the focus of a growing body of research …
Understanding the relationship between the two is the focus of a growing body of research …
[HTML][HTML] Spinal cord microglia drive sex differences in ethanol-mediated PGE2-induced allodynia
SN Alexander, OA Reed, MD Burton - Brain, Behavior, and Immunity, 2024 - Elsevier
The mechanisms of how long-term alcohol use can lead to persistent pain pathology are
unclear. Understanding how earlier events of short-term alcohol use can lower the threshold …
unclear. Understanding how earlier events of short-term alcohol use can lower the threshold …
The influence of sex on neuroimmune communication, pain, and physiology
SN Alexander, AR Green, EK Debner… - Biology of sex …, 2024 - Springer
Abstract With the National Institutes of Health's mandate to consider sex as a biological
variable (SABV), there has been a significant increase of studies utilizing both sexes …
variable (SABV), there has been a significant increase of studies utilizing both sexes …
Ketolysis is required for the proper development and function of the somatosensory nervous system
Ketogenic diets are emerging as protective interventions in preclinical and clinical models of
somatosensory nervous system disorders. Additionally, dysregulation of succinyl-CoA 3 …
somatosensory nervous system disorders. Additionally, dysregulation of succinyl-CoA 3 …
Serum fatty acid profiles in systemic lupus erythematosus and patient reported outcomes: The Michigan Lupus Epidemiology & Surveillance (MILES) Program
Introduction Despite progress in systemic lupus erythematosus (SLE) treatment, challenges
persist in medication adherence due to side effects and costs. Precision nutrition, particularly …
persist in medication adherence due to side effects and costs. Precision nutrition, particularly …
Sex-specific differences in alcohol-induced pain sensitization
SN Alexander, HS Jeong, TA Szabo-Pardi… - Neuropharmacology, 2023 - Elsevier
Pain sensitization is a phenomenon that occurs to protect tissues from damage and recent
studies have shown how a variety of non-noxious stimuli included in our everyday lives can …
studies have shown how a variety of non-noxious stimuli included in our everyday lives can …
[HTML][HTML] Loss of ATP-sensitive channel expression and function decreases opioid sensitivity in a mouse model of type 2 diabetes
C Fisher, K Johnson, M Moore, A Sadrati, JL Janecek… - bioRxiv, 2023 - ncbi.nlm.nih.gov
During diabetes, β-cell dysfunction due to loss of potassium channels sensitive to ATP,
known as K ATP channels occurs progressively over time contributing to hyperglycemia. K …
known as K ATP channels occurs progressively over time contributing to hyperglycemia. K …
To identify biomarkers associated with the transfer of diabetes combined with cancer in human genes using bioinformatics analysis
Y Li, S Gu, X Li, Q Huang - Medicine, 2023 - journals.lww.com
Currently, the incidence of diabetes mellitus is increasing rapidly, particularly in China, and
its pathogenesis is still unclear. The goal of this study was to find meaningful biomarkers of …
its pathogenesis is still unclear. The goal of this study was to find meaningful biomarkers of …
Reducing dietary branched-chain amino acids intake alleviates high-fat diet-induced pain sensitization and postoperative pain in male mice
N Lian, F Li, K Luo, Y Kang, Y Yin, S Lui, T Li… - The Journal of …, 2024 - Elsevier
Background Poor dietary intake is associated with peripheral pain sensitization and
postoperative pain. Given the limited research on diet and pain, it is essential to examine the …
postoperative pain. Given the limited research on diet and pain, it is essential to examine the …
12/15-Lipoxygenases mediate neuropathic-like pain hypersensitivity in female mice
It is estimated that chronic neuropathic pain conditions exhibit up to 10% prevalence in the
general population, with increased incidence in females. However, nonsteroidal …
general population, with increased incidence in females. However, nonsteroidal …