[HTML][HTML] The gut mycobiome in health, disease, and clinical applications in association with the gut bacterial microbiome assembly

F Zhang, D Aschenbrenner, JY Yoo, T Zuo - The Lancet Microbe, 2022 - thelancet.com
The gut mycobiome (fungi) is a small but crucial component of the gut microbiome in
humans. Intestinal fungi regulate host homoeostasis, pathophysiological and physiological …

[HTML][HTML] Microbiome and cancer

N Cullin, CA Antunes, R Straussman… - Cancer Cell, 2021 - cell.com
The human microbiome constitutes a complex multikingdom community that symbiotically
interacts with the host across multiple body sites. Host-microbiome interactions impact …

Multi-kingdom gut microbiota analyses define bacterial-fungal interplay and microbial markers of pan-cancer immunotherapy across cohorts

X Huang, M Hu, T Sun, J Li, Y Zhou, Y Yan, B Xuan… - Cell Host & Microbe, 2023 - cell.com
The effect of gut bacteria on the response to immune checkpoint inhibitors (ICIs) has been
studied, but the relationship between fungi and ICI responses is not fully understood. Herein …

[HTML][HTML] Pan-cancer analyses reveal cancer-type-specific fungal ecologies and bacteriome interactions

L Narunsky-Haziza, GD Sepich-Poore, I Livyatan… - Cell, 2022 - cell.com
Cancer-microbe associations have been explored for centuries, but cancer-associated fungi
have rarely been examined. Here, we comprehensively characterize the cancer mycobiome …

[HTML][HTML] Risk factors for invasive Candida infection in critically ill patients: A systematic review and meta-analysis

DO Thomas-Rüddel, P Schlattmann, M Pletz, O Kurzai… - Chest, 2022 - Elsevier
Background Current guidelines recommend empirical antifungal therapy in patients with
sepsis with high risk of invasive Candida infection. However, many different risk factors have …

Roles of the gut virome and mycobiome in faecal microbiota transplantation

S Lam, X Bai, AN Shkoporov, H Park, X Wu… - The Lancet …, 2022 - thelancet.com
Faecal microbiota transplantation (FMT) is an innovative approach to treat diseases that are
associated with gut dysbiosis, by transferring a healthy stool microbiota to a recipient with …

One population, multiple lifestyles: commensalism and pathogenesis in the human mycobiome

DM Proctor, RA Drummond, MS Lionakis, JA Segre - Cell host & microbe, 2023 - cell.com
Candida auris and Candida albicans can result in invasive fungal diseases. And yet, these
species can stably and asymptomatically colonize human skin and gastrointestinal tracts. To …

The role of gut mycobiome in health and diseases

L Zhang, H Zhan, W Xu, S Yan… - Therapeutic advances in …, 2021 - journals.sagepub.com
The gut microbiome comprised of microbes from multiple kingdoms, including bacteria,
fungi, and viruses. Emerging evidence suggests that the intestinal fungi (the gut …

Commensal fungi in intestinal health and disease

KS Ost, JL Round - Nature Reviews Gastroenterology & Hepatology, 2023 - nature.com
The microbiota is known to influence several facets of mammalian development, digestion
and disease. Most studies of the microbiota have focused on the bacterial component, but …

Candida–bacterial cross-kingdom interactions

KR Eichelberger, S Paul, BM Peters, JE Cassat - Trends in Microbiology, 2023 - cell.com
While the fungus Candida albicans is a common colonizer of healthy humans, it is also
responsible for mucosal infections and severe invasive disease. Understanding the …