Dendritic cells take up antigens in peripheral tissues, process them into proteolytic peptides,
and load these peptides onto major histocompatibility complex (MHC) class I and II …

Adenocarcinomas of the breast behave clinically and epidemiologically in ways that show
host resistance factors are important for outcome in addition to grade and stage of …

Over the past ten years, the identification of the critical role that dendritic cells (DCs) play in
stimulating a specific immune response has led to their use in cancer and HIV therapy …

Recent studies suggest that immunization with autologeous dendritic cells (DCs) pulsed with
tumor antigen result in protective immunity and rejection of established tumors in various …

With the continued failures of both early diagnosis and treatment options for pancreatic
cancer, it is now time to comprehensively evaluate the role of the immune system on the …

BACKGROUND The authors conducted a pilot clinical trial to explore the vaccination of
patients with late‐stage lung carcinoma with dendritic cells (DCs) pulsed with necrotic tumor …

Cytotoxic T lymphocytes (CTL) are essential effectors of the cell-mediated immune
response. The ability of CTL to specifically recognise and lyse malignant cells expressing …

Purpose: We intranodally immunized metastatic colorectal carcinoma patients, who had
failed standard chemotherapy, with dendritic cells (DCs) pulsed with HLA-A* 0201-or HLA …

BACKGROUND. Further optimization of dendritic cell (DC)‐based vaccines is required
clinically against advanced stage cancer. Given the broad range of expression levels …

Recognition of tumor-associated Ags (TAAs) on tumor cells by CTLs and the subsequent
tumor cell death are assumed to be dependent on TAA protein expression and to correlate …