Roles of the microbiota of the female reproductive tract in gynecological and reproductive health

B Zhu, Z Tao, L Edupuganti, MG Serrano… - … and Molecular Biology …, 2022 - Am Soc Microbiol
The microbiome of the female reproductive tract defies the convention that high biodiversity
is a hallmark of an optimal ecosystem. Although not universally true, a homogeneous …

The immunobiology of preterm labor and birth: intra-amniotic inflammation or breakdown of maternal–fetal homeostasis

N Gomez-Lopez, J Galaz, D Miller… - …, 2022 - rep.bioscientifica.com
In brief The syndrome of preterm labor comprises multiple established and novel etiologies.
This review summarizes the distinct immune mechanisms implicated in preterm labor and …

ISUOG Practice Guidelines: role of ultrasound in the prediction of spontaneous preterm birth

CM Coutinho, A Sotiriadis, A Odibo… - … in obstetrics & …, 2022 - pubmed.ncbi.nlm.nih.gov
ISUOG Practice Guidelines: role of ultrasound in the prediction of spontaneous preterm birth
ISUOG Practice Guidelines: role of ultrasound in the prediction of spontaneous preterm birth …

Human plasma proteome during normal pregnancy

AL Tarca, R Romero, G Bhatti, F Gotsch… - Journal of proteome …, 2022 - ACS Publications
The human plasma proteome is underexplored despite its potential value for monitoring
health and disease. Herein, using a recently developed aptamer-based platform, we profiled …

Use of cervical elastography at 18 to 22 weeks' gestation in the prediction of spontaneous preterm birth

ET Patberg, M Wells, SA Vahanian, J Zavala… - American Journal of …, 2021 - Elsevier
Background Accurate identification of the women who will have spontaneous preterm birth
continues to be a great challenge. The use of cervical elastography for prediction of preterm …

Prediction of preeclampsia throughout gestation with maternal characteristics and biophysical and biochemical markers: a longitudinal study

AL Tarca, A Taran, R Romero, E Jung… - American journal of …, 2022 - Elsevier
Background The current approach to predict preeclampsia combines maternal risk factors
and evidence from biophysical markers (mean arterial pressure, Doppler velocimetry of the …

The vaginal immunoproteome for the prediction of spontaneous preterm birth: A retrospective longitudinal study

Z Shaffer, R Romero, AL Tarca, J Galaz… - Elife, 2024 - elifesciences.org
Background: Preterm birth is the leading cause of neonatal morbidity and mortality
worldwide. Most cases of preterm birth occur spontaneously and result from preterm labor …

The amniotic fluid proteome predicts imminent preterm delivery in asymptomatic women with a short cervix

DW Gudicha, R Romero, N Gomez-Lopez, J Galaz… - Scientific reports, 2022 - nature.com
Preterm birth, the leading cause of perinatal morbidity and mortality, is associated with
increased risk of short-and long-term adverse outcomes. For women identified as at risk for …

The function and mechanism of action of uterine microecology in pregnancy immunity and its complications

L Shen, W Wang, W Hou, C Jiang, Y Yuan… - Frontiers in Cellular …, 2023 - frontiersin.org
The human microbiota influences physiology, disease, and metabolic reproduction. The
origin of uterine bacteria is controversial. The main assumption is that the germs enter the …

Preterm labor with intact membranes: a simple noninvasive method to identify patients at risk for intra-amniotic infection and/or inflammation

KJ Oh, R Romero, HJ Kim, JH Lee… - The Journal of …, 2022 - Taylor & Francis
Objective To develop a noninvasive scoring system to identify patients at high risk for intra-
amniotic infection and/or inflammation, which would reduce the need for amniocentesis …