Chronic obstructive pulmonary disease exacerbation fundamentals: diagnosis, treatment, prevention and disease impact

M MacLeod, A Papi, M Contoli, B Beghé, BR Celli… - …, 2021 - Wiley Online Library
In chronic obstructive pulmonary disease (COPD), exacerbations (ECOPD), characterized
by an acute deterioration in respiratory symptoms, are fundamental events impacting …

Cardiovascular disease and COPD: dangerous liaisons?

KF Rabe, JR Hurst, S Suissa - European Respiratory Review, 2018 - Eur Respiratory Soc
Chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD)
frequently occur together and their coexistence is associated with worse outcomes than …

Impact and prevention of severe exacerbations of COPD: a review of the evidence

DMG Halpin, M Miravitlles, N Metzdorf… - International journal of …, 2017 - Taylor & Francis
Severe exacerbations of COPD, ie, those leading to hospitalization, have profound clinical
implications for patients and significant economic consequences for society. The prevalence …

Chronic obstructive pulmonary disease and cardiac diseases. An urgent need for integrated care

S Roversi, LM Fabbri, DD Sin… - American journal of …, 2016 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) is a global health issue with high social and
economic costs. Concomitant chronic cardiac disorders are frequent in patients with COPD …

Metoprolol for the prevention of acute exacerbations of COPD

MT Dransfield, H Voelker, SP Bhatt… - … England Journal of …, 2019 - Mass Medical Soc
Background Observational studies suggest that beta-blockers may reduce the risk of
exacerbations and death in patients with moderate or severe chronic obstructive pulmonary …

The real role of β-blockers in daily cardiovascular therapy

CA Dézsi, V Szentes - American Journal of Cardiovascular Drugs, 2017 - Springer
The role of β-adrenoceptor antagonists (β-blockers) in cardiovascular therapy has been
subject to diverse trends and changes over the decades. With the advent of a wide variety of …

Clinical epidemiology of COPD: insights from 10 years of the COPDGene study

DJ Maselli, SP Bhatt, A Anzueto, RP Bowler… - Chest, 2019 - Elsevier
The Genetic Epidemiology of COPD (COPDGene) study is a noninterventional, multicenter,
longitudinal analysis of> 10,000 subjects, including smokers with a≥ 10 pack-year history …

Diagnostic and therapeutic gaps in patients with heart failure and chronic obstructive pulmonary disease

M Canepa, FME Franssen, H Olschewski, M Lainscak… - JACC: Heart Failure, 2019 - jacc.org
Heart failure (HF) and chronic obstructive pulmonary disease (COPD) coincide in a
significant number of patients. Recent population-based registries suggest that spirometry is …

Cardiovascular disease in chronic obstructive pulmonary disease: a narrative review

V Balbirsingh, AS Mohammed, AM Turner… - Thorax, 2022 - thorax.bmj.com
Patients with chronic obstructive pulmonary disease (COPD) are at increased risk of
cardiovascular disease (CVD) and concomitant disease leads to reduced quality of life …

Cardiac dysfunction during exacerbations of chronic obstructive pulmonary disease

MI MacDonald, E Shafuddin, PT King… - The Lancet …, 2016 - thelancet.com
Chronic obstructive pulmonary disease (COPD) and cardiovascular disease often coexist,
and acute cardiac events frequently occur during COPD exacerbations. Even when cardiac …