The chorioallantoic membrane as a bio-barrier model for the evaluation of nanoscale drug delivery systems for tumour therapy

E Preis, J Schulze, B Gutberlet, SR Pinnapireddy… - Advanced drug delivery …, 2021 - Elsevier
Abstract In 2010, the European Parliament and the European Union adopted a directive on
the protection of animals used for scientific purposes. The directive aims to protect animals …

The chick embryo xenograft model for malignant pleural mesothelioma: a cost and time efficient 3Rs model for drug target evaluation

SE Barnett, A Herrmann, L Shaw, EN Gash, H Poptani… - Cancers, 2022 - mdpi.com
Simple Summary Malignant pleural mesothelioma is a cancer of the lung lining, normally
caused by asbestos, that develops decades after exposure. Chemotherapy, and recently …

Iron oxide/salicylic acid nanoparticles as potential therapy for B16F10 melanoma transplanted on the chick chorioallantoic membrane

MC Predoi, I Mîndrilă, SA Buteică, ȘO Purcaru… - Processes, 2020 - mdpi.com
Unfavorable prognoses and low survival rates are specific features of metastatic melanoma
that justify the concern for the development of new therapeutic strategies. Lately …

Phenotypic switching of B16F10 melanoma cells as a stress adaptation response to Fe3O4/salicylic acid nanoparticle therapy

I Mîndrilă, A Osman, B Mîndrilă, MC Predoi… - Pharmaceuticals, 2021 - mdpi.com
Melanoma is a melanocyte-derived skin cancer that has a high heterogeneity due to its
phenotypic plasticity, a trait that may explain its ability to survive in the case of physical or …

[HTML][HTML] Partial Decellularization as a Method to Improve the Biocompatibility of Heart Tissue Implants

M Meșină, I Mîndrilă, MI Meșină-Botoran… - Current Health …, 2023 - ncbi.nlm.nih.gov
Increasing the biocompatibility of some biological implants through tissue engineering is
important for regenerative medicine, which recently has a rapid development dynamic. In …

The Chick Embryo Xenograft Model for Malignant Pleural Mesothelioma: A Cost and Time Efficient 3Rs Model for Target and Compound Evaluation

SE Barnett, A Herrmann, E Gash, H Poptani, JJ Sacco… - 2022 - preprints.org
Malignant pleural mesothelioma (MPM) has limited treatment options and poor prognosis.
Frequent inactivation of the tumour suppressors BAP1, NF2 and P16 may differentially …