Resident cardiac macrophages: Heterogeneity and function in health and disease

R Zaman, S Epelman - Immunity, 2022 - cell.com
Understanding tissue macrophage biology has become challenging in recent years due the
ever-increasing complexity in macrophage-subset identification and functional …

Status and challenges of electrical stimulation use in chronic wound healing

M Verdes, K Mace, L Margetts, S Cartmell - Current Opinion in …, 2022 - Elsevier
Non-healing wounds have led to a soaring clinical and socioeconomical need for advanced
wound-care techniques. Electrical stimulation is an emerging therapy inspired by the …

Ventricular arrhythmias in ischemic cardiomyopathy—New avenues for mechanism-guided treatment

M Amoni, E Dries, S Ingelaere, D Vermoortele… - Cells, 2021 - mdpi.com
Ischemic heart disease is the most common cause of lethal ventricular arrhythmias and
sudden cardiac death (SCD). In patients who are at high risk after myocardial infarction …

Nonmyocytes as electrophysiological contributors to cardiac excitation and conduction

A Simon-Chica, EM Wülfers… - American Journal of …, 2023 - journals.physiology.org
Although cardiac action potential (AP) generation and propagation have traditionally been
attributed exclusively to cardiomyocytes (CM), other cell types in the heart are also capable …

Effects of electrical stimulation on cytokine‐induced macrophage polarization

J Gu, X He, X Chen, L Dong, W Weng… - Journal of Tissue …, 2022 - Wiley Online Library
Macrophages have two functionalized phenotypes, M1 and M2, and the regulation of M1/M2
polarization of macrophages is critical for tissue repair. Tissue‐derived immune factors are …

The interplay between T lymphocytes and macrophages in myocardial ischemia/reperfusion injury

D Li, S Gao - Molecular and Cellular Biochemistry, 2024 - Springer
Acute myocardial infarction is one of the most important causes of death in the world,
causing a huge health and economic burden to the world. It is still a ticklish problem how to …

The contribution of ion channels to shaping macrophage behaviour

A Selezneva, AJ Gibb, D Willis - Frontiers in Pharmacology, 2022 - frontiersin.org
The expanding roles of macrophages in physiological and pathophysiological mechanisms
now include normal tissue homeostasis, tissue repair and regeneration, including neuronal …

Contractility measurements for cardiotoxicity screening with ventricular myocardial slices of pigs

R Shi, M Reichardt, DJ Fiegle, LK Küpfer… - Cardiovascular …, 2023 - academic.oup.com
Aims Cardiotoxicity is one major reason why drugs do not enter or are withdrawn from the
market. Thus, approaches are required to predict cardiotoxicity with high specificity and …

Cardiac macrophages and their effects on arrhythmogenesis

R Xia, P Tomsits, S Loy, Z Zhang, V Pauly… - Frontiers in …, 2022 - frontiersin.org
Cardiac electrophysiology is a complex system established by a plethora of inward and
outward ion currents in cardiomyocytes generating and conducting electrical signals in the …

Cardiac resident macrophages: key regulatory mediators in the aftermath of myocardial infarction

C Chen, J Wang, C Liu, J Hu - Frontiers in Immunology, 2023 - frontiersin.org
Acute myocardial infarction (MI) is a prevalent and highly fatal global disease. Despite
significant reduction in mortality rates with standard treatment regimens, the risk of heart …