Rheumatoid arthritis (RA) is a chronic immune-mediated disease that primarily affects the
synovium of diarthrodial joints. During the course of RA, the synovium transforms into a …

Rheumatoid arthritis (RA) is a systemic poly-articular chronic autoimmune joint disease that
mainly damages the hands and feet, which affects 0.5% to 1.0% of the population …

Epidemiological studies have shown a dramatic increase in the incidence and the
prevalence of allergic diseases over the last several decades. Environmental triggers …

This review covers basic aspects of histone modification and the role of posttranslational
histone modifications in the development of allergic diseases, including the immune …

The ketone bodies, especially β-hydroxybutyrate (β-HB), derive from fatty acid oxidation and
alternatively serve as a fuel source for peripheral tissues including the brain, heart, and …

Stromal cells like synovial fibroblasts gained great interest over the years, since it has
become clear that they strongly influence their environment and neighbouring cells. The …

Histone deacetylase inhibitors (HDIs) are a group of potent epigenetic drugs which have
been investigated for their therapeutic potential in various clinical disorders, including …

Systemic sclerosis (SSc) is a severe autoimmune disease that is characterized by vascular
abnormalities, immunological alterations and fibrosis of the skin and internal organs. The …

Epigenetics, an inheritable phenomenon, which influences the expression of gene without
altering the DNA sequence, offers a new perspective on the pathogenesis of hepatocellular …

Epigenetics of inflammatory arthritis : Current Opinion in Rheumatology Epigenetics of
inflammatory arthritis : Current Opinion in Rheumatology Log in or Register Subscribe to …