Virus-like particles (VLPs) are a class of subunit vaccines that differentiate themselves from
soluble recombinant antigens by stronger protective immunogenicity associated with the …

Viral infectious diseases threaten human health and global stability. Several vaccine
platforms, such as DNA, mRNA, recombinant viral vectors, and virus-like particle-based …

Recombinant virus-like particle-based vaccines are composed of viral structural proteins
and mimic authentic native viruses but are devoid of viral genetic materials. They are the …

Virus-like particles (VLPs) can be spontaneously self-assembled by viral structural proteins
under appropriate conditions in vitro while excluding the genetic material and potential …

The building block of hepatitis C virus (HCV) nucleocapsid, the core protein, together with
viral RNA, is composed of different domains involved in RNA binding and homo …

Hepatitis C virus (HCV) has been recognized as a major cause of chronic liver diseases
worldwide. Molecular studies of the virus became possible with the successful cloning of its …

Hepatitis C virus (HCV) infection afflicts more than 170 million people worldwide, with the
great majority of patients with acute hepatitis C developing chronic HCV infection. It can …

Infection with hepatitis C virus (HCV), which is distributed worldwide, often becomes
persistent, causing chronic hepatitis, cirrhosis, and hepatocellular carcinoma. For many …

The specific packaging of the hepatitis C virus (HCV) genome is hypothesised to be driven
by Core-RNA interactions. To identify the regions of the viral genome involved in this …

The assembly of hepatitis C virus (HCV) is poorly understood, largely due to the lack of
mammalian cell culture systems that are easily manipulated and produce high titers of virus …