[HTML][HTML] A guide to vaccinology: from basic principles to new developments
AJ Pollard, EM Bijker - Nature Reviews Immunology, 2021 - nature.com
Immunization is a cornerstone of public health policy and is demonstrably highly cost-
effective when used to protect child health. Although it could be argued that immunology has …
effective when used to protect child health. Although it could be argued that immunology has …
Nanotechnology approaches for global infectious diseases
Infectious diseases are a major driver of morbidity and mortality globally. Treatment of
malaria, tuberculosis and human immunodeficiency virus infection are particularly …
malaria, tuberculosis and human immunodeficiency virus infection are particularly …
[HTML][HTML] Efficacy and immunogenicity of R21/Matrix-M vaccine against clinical malaria after 2 years' follow-up in children in Burkina Faso: a phase 1/2b randomised …
MS Datoo, HM Natama, A Somé, D Bellamy… - The Lancet Infectious …, 2022 - thelancet.com
Background Malaria is a leading cause of morbidity and mortality worldwide. We previously
reported the efficacy of the R21/Matrix-M malaria vaccine, which reached the WHO-specified …
reported the efficacy of the R21/Matrix-M malaria vaccine, which reached the WHO-specified …
[HTML][HTML] Efficacy of a low-dose candidate malaria vaccine, R21 in adjuvant Matrix-M, with seasonal administration to children in Burkina Faso: a randomised controlled …
Background Stalled progress in controlling Plasmodium falciparum malaria highlights the
need for an effective and deployable vaccine. RTS, S/AS01, the most effective malaria …
need for an effective and deployable vaccine. RTS, S/AS01, the most effective malaria …
Seasonal malaria vaccination with or without seasonal malaria chemoprevention
D Chandramohan, I Zongo, I Sagara… - … England Journal of …, 2021 - Mass Medical Soc
Background Malaria control remains a challenge in many parts of the Sahel and sub-Sahel
regions of Africa. Methods We conducted an individually randomized, controlled trial to …
regions of Africa. Methods We conducted an individually randomized, controlled trial to …
The role of bacterial vaccines in the fight against antimicrobial resistance: an analysis of the preclinical and clinical development pipeline
I Frost, H Sati, P Garcia-Vello… - The Lancet …, 2023 - thelancet.com
Vaccines can be highly effective tools in combating antimicrobial resistance as they reduce
infections caused by antibiotic-resistant bacteria and antibiotic consumption associated with …
infections caused by antibiotic-resistant bacteria and antibiotic consumption associated with …
[HTML][HTML] Safety and efficacy of a monoclonal antibody against malaria in Mali
K Kayentao, A Ongoiba, AC Preston… - … England Journal of …, 2022 - Mass Medical Soc
Background CIS43LS is a monoclonal antibody that was shown to protect against controlled
Plasmodium falciparum infection in a phase 1 clinical trial. Whether a monoclonal antibody …
Plasmodium falciparum infection in a phase 1 clinical trial. Whether a monoclonal antibody …
Low-dose subcutaneous or intravenous monoclonal antibody to prevent malaria
RL Wu, AH Idris, NM Berkowitz, M Happe… - … England Journal of …, 2022 - Mass Medical Soc
Background New approaches for the prevention and elimination of malaria, a leading cause
of illness and death among infants and young children globally, are needed. Methods We …
of illness and death among infants and young children globally, are needed. Methods We …
Emerging concepts and technologies in vaccine development
Despite the success of vaccination to greatly mitigate or eliminate threat of diseases caused
by pathogens, there are still known diseases and emerging pathogens for which the …
by pathogens, there are still known diseases and emerging pathogens for which the …
A monoclonal antibody for malaria prevention
MR Gaudinski, NM Berkowitz, AH Idris… - … England Journal of …, 2021 - Mass Medical Soc
Background Additional interventions are needed to reduce the morbidity and mortality
caused by malaria. Methods We conducted a two-part, phase 1 clinical trial to assess the …
caused by malaria. Methods We conducted a two-part, phase 1 clinical trial to assess the …