There has been remarkable insight into the importance of platelets in a wide range of
pathophysiologic events, including inflammation and cancer progression. Thrombocytosis in …

The presence of platelets in association with cancer deposits has been recognised for over
100 years; however, the recognition of a two-way interaction has been more recent. The link …

Background Systemic activation of hemostasis is frequently observed in cancer patients,
even in the absence of thrombosis. Moreover, this activation has been implicated in tumor …

Anemia affects one-fourth of the world's population, and iron deficiency is the predominant
cause. Anemia is associated with chronic fatigue, impaired cognitive function, and …

There is increasing evidence that platelets play an important role in the process of tumor
angiogenesis. Thrombocytosis is a frequent finding in cancer patients (10–57%). Although …

In addition to its primary role in hemostasis and blood coagulation, thrombin is a potent
mitogen capable of inducing cellular functions. Therefore, it should come as no surprise that …

Background: In cancer patients, laboratory parameters that predict venous
thromboembolism (VTE) are scarce. Increased platelet count has been found to be a risk …

Purpose Patients with cancer are at increased risk of venous thromboembolism (VTE).
Laboratory tests measuring the overall thrombophilic tendency might be useful to assess …

The “hypercoagulable state” of malignancy is due to a complex interaction of tumor cells and
their products with host cells, leading to various degrees of impairment of the normal …

Nearly all patients with cancer manifest laboratory evidence of hypercoagulability and some
develop clinical thromboembolic disease (TED). Routine laboratory studies of blood …