Biopolymer-based functional composites for medical applications

SB Park, E Lih, KS Park, YK Joung, DK Han - Progress in Polymer Science, 2017 - Elsevier
Over the last decade, numerous biopolymers have received more attention in medical
applications involving novel biomaterials because of their biocompatibility, biodegradability …

Biomimetic architectures for peripheral nerve repair: a review of biofabrication strategies

PA Wieringa, AR Gonçalves de Pinho… - Advanced …, 2018 - Wiley Online Library
Biofabrication techniques have endeavored to improve the regeneration of the peripheral
nervous system (PNS), but nothing has surpassed the performance of current clinical …

Bioactive silk‐based nerve guidance conduits for augmenting peripheral nerve repair

A Magaz, A Faroni, JE Gough, AJ Reid… - Advanced …, 2018 - Wiley Online Library
Repair of peripheral nerve injuries depends upon complex biology stemming from the
manifold and challenging injury‐healing processes of the peripheral nervous system. While …

Advances in nerve guidance conduit-based therapeutics for peripheral nerve repair

WA Lackington, AJ Ryan, FJ O'Brien - ACS Biomaterials Science …, 2017 - ACS Publications
Peripheral nerve injuries have high incidence rates, limited treatment options and poor
clinical outcomes, rendering a significant socioeconomic burden. For effective peripheral …

Mechanotransduction of neural cells through cell–substrate interactions

JM Stukel, RK Willits - Tissue Engineering Part B: Reviews, 2016 - liebertpub.com
Neurons and neural stem cells are sensitive to their mechanical and topographical
environment, and cell–substrate binding contributes to this sensitivity to activate signaling …

[PDF][PDF] Cellular contact guidance emerges from gap avoidance

ABC Buskermolen, T Ristori, D Mostert… - Cell Reports Physical …, 2020 - cell.com
In the presence of anisotropic biochemical or topographical patterns, cells tend to align in
the direction of these cues—a widely reported phenomenon known as" contact guidance." …

Gelatin/nanoceria nanocomposite fibers as antioxidant scaffolds for neuronal regeneration

A Marino, C Tonda-Turo, D De Pasquale… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Background The design of efficient nerve conduits able to sustain the axonal outgrowth and
its guidance towards appropriate targets is of paramount importance in nerve tissue …

Applications of nanotechnology for regenerative medicine; healing tissues at the nanoscale

Y Yang, A Chawla, J Zhang, A Esa, HL Jang… - … of regenerative medicine, 2019 - Elsevier
Regenerative medicine involves the development of methods to repair and replace
diseased or damaged cells, tissues, or organs to restore or establish normal tissue functions …

Neuronal differentiation on anisotropic substrates and the influence of nanotopographical noise on neurite contact guidance

I Tonazzini, S Meucci, P Faraci, F Beltram, M Cecchini - Biomaterials, 2013 - Elsevier
Cells are exposed to specific directional physical signals determined by the micro/nano-
environment that in vivo coexist with some degree of topographical noise. Particularly in the …

Neoglucosylated collagen matrices drive neuronal cells to differentiate

L Russo, A Sgambato, M Lecchi, V Pastori… - ACS Chemical …, 2014 - ACS Publications
Despite the relevance of carbohydrates as cues in eliciting specific biological responses,
glycans have been rarely exploited in the study of neuronal physiology. We report thereby …