SRF expedites metastasis and modulates the epithelial to mesenchymal transition by regulating miR-199a-5p expression in human gastric cancer

X Zhao, L He, T Li, Y Lu, Y Miao, S Liang… - Cell Death & …, 2014 - nature.com
Dysregulation of transcription factors (TFs) is associated with tumor progression, but little is
known about TF expression patterns in the context of gastric cancer (GC) metastasis. Using …

CD83-stimulated monocytes suppress T-cell immune responses through production of prostaglandin E2

L Chen, Y Zhu, G Zhang, C Gao… - Proceedings of the …, 2011 - National Acad Sciences
CD83 is commonly known as a specific marker for mature dendritic cells. It has been shown
to be important for CD4+ T-cell development in the thymus. However, its function in the …

Transcription factor CUTL1 is a negative regulator of drug resistance in gastric cancer

T Li, H Wang, Y Sun, L Zhao, Y Gang, X Guo… - Journal of Biological …, 2013 - ASBMB
Gastric cancer is one of the leading causes of malignancy-related mortality worldwide, and
drug resistance hampered the clinical efficacy of chemotherapy. To better understand the …

Microarray profiling of monocytic differentiation reveals miRNA‐mRNA intrinsic correlation

J Wang, G Xiang, K Mitchelson… - Journal of cellular …, 2011 - Wiley Online Library
MiRNAs (microRNAs) are small non‐coding RNAs involved in mammalian gene expression
of cellular processes including differentiation, apoptosis and cancer development. Both …

[HTML][HTML] An integrated approach for the identification of HNF4α-centered transcriptional regulatory networks during early liver regeneration

H Jiao, Y Zhu, S Lu, Y Zheng, H Chen - Cellular Physiology and …, 2015 - karger.com
Background/Aims: Hepatocyte nuclear factor-4α (HNF4α), the liver enriched transcription
factor (TF), is one of the major regulators of hepatocyte differentiation and proliferation …

[HTML][HTML] XAGE‑1b expression is associated with the diagnosis and early recurrence of hepatocellular carcinoma

Z Pan, B Tang, Z Hou, J Zhang… - Molecular and …, 2014 - spandidos-publications.com
XAGE‑1b is a 470 bp transcript of the XAGE‑1 gene, which belongs to the cancer‑testis
antigens that exhibit a restricted pattern of expression in normal tissues. Recently, the …

An integrated approach for the identification of USF1-centered transcriptional regulatory networks during liver regeneration

H Chen, S Lu, J Zhou, Z Bai, H Fu, X Xu, S Yang… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Liver regeneration after partial hepatectomy (PH) is a synchronized process that is precisely
controlled by system-wide transcriptional regulatory networks. To clarify the transcriptional …

Sodium ferulate modified gene expression profile of oxidized low-density lipoprotein-stimulated human umbilical vein endothelial cells

D Zhang, Z Bi, Y Li, H Zheng, L Li… - Journal of …, 2009 - journals.sagepub.com
Oxidized low-density lipoprotein (ox-LDL) is known to trigger vascular injury in
atherosclerosis development. Sodium ferulate is an effective component from Chinese …

Cardiac lineage selection: integrating biological complexity into computational models

A Foley - Wiley Interdisciplinary Reviews: Systems Biology and …, 2009 - Wiley Online Library
The emergence of techniques to study developmental processes using systems biology
approaches offers exciting possibilities for the develpmental biologist. In particular cardiac …

PCR DNA-array profiling of DNA-binding transcription factor activities in adult mouse tissues

Y Sun, J Cheng, KR Mitchelson - PCR Protocols, 2011 - Springer
Differential gene expression is tightly controlled by transcription factors (TFs), which bind
close to target genes and interact together to activate and coregulate transcription …